94174 Results for: "Benzyltributylammonium+bromide&pageNo=9"
L-858051 ≥92% (by HPLC)
Supplier: Enzo Life Sciences
Adenylate cyclase activator.
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Sp-5,6-dichloro-cBIMPS ≥98% (by HPLC)
Supplier: Enzo Life Sciences
PKA activator.
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SB216763 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.
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Sodium 4-phenylbutyrate ≥98% (by UHPLC)
Supplier: Enzo Life Sciences
Weak histone deacetylase (HDAC) inhibitor. Induces differentiation, growth arrest and apoptosis in a number of cell lines. Protects against cerebral ischemic injury and displays neuroprotective effect in a mouse model of Huntington’s disease. Anti-neoplastic agent and transcriptional regulator. Also acts as an inducer of tumor cytostasis and differentiation. Shows chemical chaperone activity.
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5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside ≥99% (by TLC)
Supplier: Enzo Life Sciences
AMPK activator
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2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione ≥98% (by HPLC)
Supplier: Enzo Life Sciences
A potent and selective inhibitor of Cdc25 phosphatase (Ki's for Cdc25A, B and C are 32, 96 and 40 nM respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.
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Ar231453 ≥98% (by HPLC), yellow solid
Supplier: Enzo Life Sciences
GPR119 activator.
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cis-5,8,11-Eicosatrienoic acid ≥97% (by HPLC), colourless oil
Supplier: Enzo Life Sciences
Immunomodulatory and anti-inflammatory effects.
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21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]triene-3,20-dione maleate salt ≥98% (by TLC)
Supplier: Enzo Life Sciences
Blocks lipid peroxidation
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N-Arachidonylglycine ≥98% (by TLC)
Supplier: Enzo Life Sciences
FAAH inhibitor
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Geldanamycin ≥98% (by TLC) (conjugated to FITC)
Supplier: Enzo Life Sciences
A novel geldanamycin fluorescent probe that may be used in a fluorescence polarization assay for HSP90 inhibitors. May also be used for detection of cell surface HSP90.
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Midostaurin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.
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4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione ≥95% (by TLC)
Supplier: Enzo Life Sciences
Novel inhibitor of ubiquitin C-terminal hydrolase L3 (IC50 = 0.6µM). Displays 125-fold greater selectivity over UCH-L1 (IC50 = 75µM).
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Ko143 ≥96% (by HPLC)
Supplier: Enzo Life Sciences
Analog of the fungal toxin fumitremorgin C. Potent and selective inhibitor of the breast cancer resistance protein multidrug transporter (BCRP, EC90=26nM). Highly effective for increasing the intracellular drug accumulation and reversing BCRP-mediated multidrug resistance yet has little activity against P-glycoprotein, multidrug resistance-associated protein (MRP1) and other known drug transporters. In mouse models Ko143 was able to restore the intracellular accumulation and abolish the directionality in net flux of dasatinib. It is a highly useful tool for the identification of drug transport processes in complex experimental systems.
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5,8,11,14-Eicosatetraynoic acid ≥98%
Supplier: Enzo Life Sciences
Arachidonic acid uptake inhibitor
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Chaetomellic acid A ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).
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Lovastatin ≥98% (by TLC)
Supplier: Enzo Life Sciences
HMG-CoA reductase inhibitor
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NSC 23766 ≥99% (by HPLC)
Supplier: Enzo Life Sciences
Cell-permeable, reversible, and selective Rac1 inhibitor.
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ELISA KIT HUMAN TETANUS TOXOID IGG 1 * 96 Tests
Supplier: Enzo Life Sciences
ELISA KIT HUMAN TETANUS TOXOID IGG 1 * 96 Tests
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Vented Millex® GS Syringe Filter
Supplier: Merck
Vented Millex®-GS filter units are syringe filters for sterilisation of low volume aqueous solutions where venting is desired.
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3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥98%
Supplier: Enzo Life Sciences
PKC inhibitor
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Aristolochic acid ≥97%
Supplier: Enzo Life Sciences
Reversible noncompetitive PLA2 inhibitor.
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Rosmarinic acid ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Rosmarinic acid ≥98% (by HPLC)
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(-)-Epigallocatechin gallate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of NOS, telomerase and Dnmt
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Aminopurvalanol A ≥97% (by 1H-NMR)
Supplier: Enzo Life Sciences
CDK/cyclin inhibitor
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Ratjadone A (synthetic) ≥95%
Supplier: Enzo Life Sciences
Ratjadone A (synthetic) ≥95%
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Tryptanthrin ≥98% (by 1H-NMR, HPLC)
Supplier: Enzo Life Sciences
Inhibitor of prostaglandin and leukotriene synthesis.
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SC-236 ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Highly selective and potent inhibitor of cyclooxygenase-2 (IC50=10nM for COX-2 versus IC50=17.8µM for COX-1) with antitumor properties. Exhibits longer half-life time and reduced gastric toxicity in fasting rat model. Has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. Potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.