118870 Results for: "9-Cyano-N,N,N\u2032-triethylpyronine-N\u2032-caproic+acid+N-hydroxysuccinimide+ester+chloride"

Supplier: Welch by Gardner Denver

The MXPC SERIES comes from the latest generation of Welch MPCpro diaphragm pumps to provide improved performance, particularly in the application critical range. The ultimate vacuum of 5 or 1,5 mbar with significant design improvements to directly influence the process flow and the repeatability. The new Single Piece Diaphragm (SPD) design provides increased chemical resistance and easier servicing. These models are ideal for applications where a high pumping speed, fast pump down time and deep ultimate vacuum are required, such as vacuum ovens, rotary evaporators and vacuum concentrators.

Supplier: ProSci Inc.

Tumor necrosis factor receptor superfamily, member 6 isoform 1; apoptosis antigen 1; Fas antigen; APO-1 cell surface antigen. This protein is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-κB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. ** Cat.N

Supplier: GETINGE LIFE SCIENCES

HOSE VERSILIC DIAM.6X10 LG 2500 1 * 1 items

Supplier: Roth Carl

SEKUROKA COLLECTION TRAY 20 L 1 * 1 items

Supplier: Roth Carl

PYRACIDOSORB ABSORBENT 1 * 5 kg

Supplier: Lovibond Tintometer

Two spectrophotometric colorimeters that each include several of the popular scales that meet the requirements of objective colour analysis of oils, chemicals, fuels and other transparent products. The PFXi 950 instruments are rugged colorimeters with fabricated steel housings, which function equally as QC instruments within the laboratory or on 24-hour operation in a production environment. The accuracy and repeatability of the colour data provided by these colorimeters ensures consistency in colour measurement, giving processors the confidence needed to make important decisions regarding raw materials and refining operations.

Supplier: Corning

Corning® Synthegel™ 3D matrices are chemically defined peptides that self assemble into nanofibers which crosslink to form tuneable hydrogels. These hydrogels provide a robust and reproducible microenvironment for 3D culture of physiological spheroids and hiPS cells. The Synthegel™ matrix kits provide negligible variability and a more controlled substrate for in vivo-like 3D cell culture. Such a platform is needed for cancer research, stem cell research, and drug screening in a 3D format.

Supplier: ProSci Inc.

ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signallling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumour cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.

Supplier: GASTEC

GASTUBE HYDROGEN CYANIDE MR 17-2400PPM 1 * 10 items

Supplier: SEMADENI

MESSKANNE 1000ML, PP 1 * 1 items

Supplier: Biosensis

BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

Supplier: ECOLINE NV SA

TISSU HIGHEXTRASMOOTH 55CELL 45POL 68GSM 1 * 5 Roll

Supplier: ECOLINE NV SA

TISSU PROFITEXTRASMOOTH 55CELL 45POL 68 1 * 5 Roll

Supplier: Biosensis

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. FUNCTION: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted protein. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. DISEASE: Defects in GDNF may be a cause of Hirschsprung disease (HSCR). In association with mutations of RET gene, defects in GDNF may be involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. DISEASE: Defects in GDNF are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.

Supplier: SEMADENI

BOTTLE CENTRIFUGE PP/PE 1000 ML 1 * 1 items

Supplier: CUSTOM MADE CHEMICALS LAB

53 components mix 1 * 2 Ampoul

Supplier: Lovibond Tintometer

The PFXi 995 spectrophotometers are top of the range, versatile instruments that offer comprehensive colour data requirements for either the Petrochemicals industry or the Food and Chemicals industries for edible oils, fats, chemicals etc. The PFXi 995 and PFXi 995/P provide objective, unbiased colour data according to a comprehensive range of established industry scales, spectral data and CIE values. They are ideal for companies that process a broad selection of product types with varied colour specifications, particularly in central test facilities or in independent testing laboratories. The instruments are easily customised to display only those scales of interest to the user.

Supplier: VELP SCIENTIFIC

The FIWE Advance is a fully automatic analyser for Crude and Detergent Fibre determination according to official reference methods. State of the art technology ensures safety, premium remote connectivity and a unique user experience. FIWE Advance Load and Go operation, requires minimum operator time, just 2 minutes, to improve productivity.

Supplier: IKA

EasySyn is the reactor system for organic or aqueous syntheses, and the only reactor system for which you can get all the complementary components from a single source: Overhead stirrers, circulators, vacuum pumps and controllers, sensors and automation software. All from IKA and all perfectly matched to each other. With its double-walled reactor vessels from 500 to 5000 ml, EasySyn is a medium-sized and very flexible upscaling system. It ensures safe and reproducible chemical reactions.

Supplier: Thermo Orion

The Thermo Scientific™ Orion Star™ T910 pH titrators are designed to increase your laboratory productivity by automating titrations. Our core electrochemistry technology is integrated with a state-of-the-art reagent dispensing system to create modern, simplified automated titrators designed to make performing titrations easier, more reliable and more reproducible than manual titrations.

Supplier: MIELE

These cleaning and disinfection machines with integrated drying system and drawer have been designed for the treatment of clinical instruments and for washing laboratory glassware in research laboratories, biology and pharmaceutical industries. The new PG 85 range offers a wide range of innovations such as freely programmable PROFITRONIC+ controls, PerfectSpeed spray arm monitoring, temperature independent PerfectFlow dispensing control on the basis of ultrasound as well as PerfectPureSensor conductivity metering.

Supplier: LGC Standards PROMOCHEM

PHENYLCYCLOHEXYLGLYCOLIC AICD 1 * 25 mg

Supplier: PanReac AppliChem

Sea Sand for analysis 1 * 5 kg

Supplier: PanReac AppliChem

Sea Sand for analysis 1 * 1 kg

Supplier: Sartorius

The Vivacon 500 PCR Grade units have been treated with a dual-cycle ethylene oxide (ETO) gas process to ensure they are sterile to a safety assurance level of 106 and free of detectable human genomic DNA contamination. Tests were performed with a qP 1 * 100 items

Supplier: Sartorius

The Vivacon 500 PCR Grade units have been treated with a dual-cycle ethylene oxide (ETO) gas process to ensure they are sterile to a safety assurance level of 106 and free of detectable human genomic DNA contamination. Tests were performed with a qP 1 * 100 items

Supplier: THERMO LABSYSTEMS LIFE SCIENCE

Varioskan™ LUX comes equipped with a range of measurement technologies including absorbance, fluorescence intensity and FRET as standard, and with optional luminescence, AlphaScreen and time-resolved fluorescence (TRF) modules. The instrument selects the measurement wavelength using filters or monochromators, depending on which is optimal for each measurement technology.

Supplier: LGC Standards PROMOCHEM

KETOPROFEN IMP. H (EP): 3-(CYANOMETH 1 * 100 mg

Supplier: CUSTOM MADE CHEMICALS LAB

15 COMPONENTS MIX 1 * 5 Ampoul

Supplier: Corning

AxyPrep Mag Viral NA-96 Prep 1 * 1 items