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118854 results for "9-Cyano-N,N,N\u2032-triethylpyronine-N\u2032-caproic+acid+N-hydroxysuccinimide+ester+chloride"

118854 Results for: "9-Cyano-N,N,N\u2032-triethylpyronine-N\u2032-caproic+acid+N-hydroxysuccinimide+ester+chloride"

Rat CaMKII beta ELISA Kit

Rat CaMKII beta ELISA Kit

Supplier: ANTIBODIES.COM

Rat CaMKII beta ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat CaMKII beta in serum, plasma, tissue homogenates, and other biological fluids.

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Monkey beta Nerve Growth Factor ELISA Kit

Monkey beta Nerve Growth Factor ELISA Kit

Supplier: ANTIBODIES.COM

Monkey beta Nerve Growth Factor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of monkey beta Nerve Growth Factor in serum, plasma, tissue homogenates, and other biological fluids.

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PMA enhancer for Gram negative bacteria solution 5X

Supplier: Biotium

PMA Enhancer for Gram Negative Bacteria was designed to improve PMA- and PMAxx™-mediated discrimination between live and dead gram-negative bacteria.

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Human NF-kB p65 ELISA Kit

Human NF-kB p65 ELISA Kit

Supplier: ANTIBODIES.COM

Human NF-kB p65 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human NF-kB p65 in serum, plasma, tissue homogenates, and other biological fluids.

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Porcine beta Nerve Growth Factor ELISA Kit

Porcine beta Nerve Growth Factor ELISA Kit

Supplier: ANTIBODIES.COM

Porcine beta Nerve Growth Factor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of porcine beta Nerve Growth Factor in serum, plasma, tissue homogenates, and other biological fluids.

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Rat Angiotensin II Type 2 Receptor ELISA Kit

Rat Angiotensin II Type 2 Receptor ELISA Kit

Supplier: ANTIBODIES.COM

Rat Angiotensin II Type 2 Receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat Angiotensin II Type 2 Receptor in serum, plasma, tissue homogenates, and other biological fluids.

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Rat alpha smooth muscle Actin ELISA Kit

Rat alpha smooth muscle Actin ELISA Kit

Supplier: ANTIBODIES.COM

Rat alpha smooth muscle Actin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat alpha smooth muscle Actin in serum, plasma, tissue homogenates, and other biological fluids.

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Anti-PD-L1 Rabbit Polyclonal Antibody

Anti-PD-L1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

PDL-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. PDL-1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PDL-1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts. At least two isoforms of PDL-1 are known to exist; this antibody is specific to the larger isoform. PDL-1 antibody has no cross-reactivity to PDL-2.

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Anti-AQP2 Rabbit Polyclonal Antibody

Anti-AQP2 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans (Iolascon et al.,2007). A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells (van Balkom et al., 2002). Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking (Hoffert et al., 2007).

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Sample Collection Cards, LeafSaver

Supplier: Ahlstrom-Munksjö

This LeafSaver is ideal for simple collection, transportation and ambient-temperature storage of plants, fungi, insects and parasites.

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Blood collecting systems, S-Monovette® CPDA1

Supplier: SARSTEDT

S-Monovette® is a blood collection system that combines two blood collection techniques – aspiration and vacuum. The S-Monovette® is suitable for all vein conditions and achieves an optimal sample quality, thereby producing the best results. The aspiration technique is a gentle technique for routine blood collection. Using the vacuum technique, a 'fresh' vacuum is always available.

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Mouse alpha smooth muscle Actin ELISA Kit

Mouse alpha smooth muscle Actin ELISA Kit

Supplier: ANTIBODIES.COM

Mouse alpha smooth muscle Actin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse alpha smooth muscle Actin in serum, plasma, tissue homogenates, and other biological fluids.

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Human non-muscle Myosin IIB/MYH10 ELISA Kit

Human non-muscle Myosin IIB/MYH10 ELISA Kit

Supplier: ANTIBODIES.COM

Human non-muscle Myosin IIB/MYH10 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human non-muscle Myosin IIB/MYH10 in serum, plasma, tissue homogenates, and other biological fluids.

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Mouse alpha 2a Adrenergic Receptor ELISA Kit

Mouse alpha 2a Adrenergic Receptor ELISA Kit

Supplier: ANTIBODIES.COM

Mouse alpha 2a Adrenergic receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse alpha 2a Adrenergic receptor in serum, plasma, tissue homogenates, and other biological fluids.

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One-Step Lumitein™ protein gel stain

Supplier: Biotium

One-Step Lumitein™ Protein Gel Stain is a ready-to-use luminescent red protein gel stain. It is a dramatically improved version of our original Lumitein™ protein gel stain in terms of convenience and safety. One-Step Lumitein™ can detect as little as approximately 1-10 ng of protein per band.

   Sustainable Options Available
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Recycling solution for centrifuge tubes and rigid lab plastics

Recycling solution for centrifuge tubes and rigid lab plastics

Supplier: TERRACYCLE

A Zero Waste Box™ is a complete and convenient solution which includes the storage, shipping and recycling of a particular type of waste that isn’t currently recycled through local councils or traditional recycling facilities.

   Sustainable Options Available
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Recycling solution for protective eyewear, Zero Waste Box™

Recycling solution for protective eyewear, Zero Waste Box™

Supplier: TERRACYCLE

A Zero Waste Box™ is a complete and convenient solution which includes the storage, shipping and recycling of a particular type of waste that isn’t currently recycled through local councils or traditional recycling facilities.

   Sustainable Options Available
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Rat NF-kB p65 ELISA Kit

Rat NF-kB p65 ELISA Kit

Supplier: ANTIBODIES.COM

Rat NF-kB p65 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat NF-kB p65 in serum, plasma, tissue homogenates, and other biological fluids.

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Human HCF-1/Host Cell Factor C1 ELISA Kit

Human HCF-1/Host Cell Factor C1 ELISA Kit

Supplier: ANTIBODIES.COM

Human HCF-1/Host Cell Factor C1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human HCF-1/Host Cell Factor C1 in serum, plasma, tissue homogenates, and other biological fluids.

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Anti-GAP43 Rabbit Polyclonal Antibody

Anti-GAP43 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by Protein Kinase C modulates the interaction of GAP-43 with actin.

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Anti-NALP3 Rabbit Polyclonal Antibody

Anti-NALP3 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

NALP3 Antibody: NALP3, a member of Nod-like receptors, has a crucial role in inflammation and immunity and may be a proximal sensor of cellular stress and danger signals. NALP3 forms a caspase-1 activating molecular complex termed the inflammasome. The inflammasome allows activation of IL-1 beta , the key player of the inflammation and fever. NALP3 gene encodes a pyrin like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine rich repeat (LRR) motif. NALP3 protein interacts with apoptosis associated speck like protein containing a CARD and may function as an inducer of apoptosis and an activator of NF-kappa B signaling. Defects in NALP3 have been associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).

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Anti-TPH2 Rabbit Polyclonal Antibody

Anti-TPH2 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin) (Martinez et al., 2001). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II) (Jiang et al., 2000; Johansen et al., 1996). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2 (McKinney et

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Anti-CREB1 Rabbit Polyclonal Antibody

Anti-CREB1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

It is well known that the control of gene expression involves activation of protein kinase cascades that regulate transcription factors within the nucleus (Karin and Hunter, 1995). The cyclic AMP response element binding protein (CREB) is one of the best characterized stimulus-induced transcription factors (Montminy, 1997). This transcription factor is a component of intracellular signaling events that regulate a wide range of biological functions, from spermatogenesis to circadian rhythms and memory (Shaywitz and Greenberg, 1999; Silva et al., 1998). A variety of protein kinases including protein kinase A (PKA), mitogenactivated protein kinases (MAPKs), and Ca2+/calmodulin-dependent protein kinases (CaMKs) phosphorylate CREB at serine 133 (Ser133), and phosphorylation of Ser133 are required for CREB-mediated transcription (Johannessen et al., 2004; Kornhauser et al., 2002).

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Service and retail wiping paper, centrefeed roll, WypAll® Reach™

Service and retail wiping paper, centrefeed roll, WypAll® Reach™

Supplier: KIMBERLY CLARK

WypAll® L10 centrefeed roll is blue roll designed for light-duty hygiene wiping and designed for use in retail and service environments. Compatible with the portable WypAll® Reach™ dispenser (115-2528) which ensures rolls remain enclosed to help prevent against transmission of food-borne bacteria.

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Microplate readers, multi-mode, SpectraMax® i3x

Microplate readers, multi-mode, SpectraMax® i3x

Supplier: MOLECULAR DEVICES

The SpectraMax® i3x multi-mode microplate reader is a configurable, versatile microplate reader that evolves with your future needs and allows you to investigate every aspect of a cellular pathway. The SpectraMax i3x microplate reader measures absorbance, luminescence and fluorescence as standard, and provides the flexibility to add novel detection capabilities without the need for service engineers or costly downtime - it grows with you as your research evolves.

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BL21 competent cells

Supplier: AGILENT

BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

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Food and hygiene wiping paper, centrefeed roll, WypAll® Reach™

Food and hygiene wiping paper, centrefeed roll, WypAll® Reach™

Supplier: KIMBERLY CLARK

WypAll® L10 centrefeed roll, designed for light-duty hygiene wiping and perfect for tasks like cleaning food preparation and service surfaces. Compatible with the portable WypAll® Reach™ dispenser (115-2528) which ensures rolls remain enclosed to help prevent against transmission of food-borne bacteria.

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Anti-RAE1 Rabbit Polyclonal Antibody

Anti-RAE1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Anti-RAE1 Rabbit Polyclonal Antibody

Anti-RAE1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Water purification system, WaterPro® BT

Water purification system, WaterPro® BT

Supplier: LABCONCO

The WaterPro® BT Water Purification System produces both RO and Type I water directly from tap water. The benchtop design is compact and lightweight so it can easily be transported from lab to lab. The Filter Pack (required, sold separately) bundles all water filter technologies into one convenient twin cartridge package so installation is simple.

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