87938 Results for: "6-Methyl-2-(trifluoromethyl)pyrimidin-4(3H)-one"

Supplier: ProSci Inc.

Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function.

Supplier: SIOEN

This high performance jacket is made of a 2-layer laminated fabric consisting of 60% FR Modacryl and 40% cotton (& AST) ripstop with PU laminate. The jacket features a fixed flame-retardant cotton lining but other fleeces and lining can be zipped in at any time.

Supplier: MOLNLYCKE HEALTH CARE

These sterile, cleanroom gloves with beaded anti-slip cuffs and curved fingers are suitable for use in aseptic and Class 100 (ISO 5)/EU GMP Grade A environments. Recommended to be worn in combination with the Biogel® PI Tech Indicator Underglove to form a Breach Indication System.

Supplier: ANTIBODIES.COM

Human ZO1 Tight Junction Protein ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human ZO1 Tight Junction Protein in serum, plasma, and other biological fluids.

Supplier: ANTIBODIES.COM

Human Serum Response Factor SRF ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Serum Response Factor SRF in serum, plasma, and other biological fluids.

Supplier: ANTIBODIES.COM

Mouse Retinoic acid Receptor gamma ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse Retinoic acid Receptor gamma in serum, plasma, and other biological fluids.

Supplier: ANTIBODIES.COM

Human IL-36 alpha/IL-1F6 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL-36 alpha/IL-1F6 in serum, plasma, and other biological fluids.

Supplier: Thermo Scientific

The manual defrost, high-performance freezers are designed for applications in which even slight intermittent coil warming during auto defrost cannot be tolerated. The Series’ V-drive technology is designed to provide temperature uniformity that continually adapts to user patterns, offering significant energy savings without compromising protection.

Supplier: Whatman products (Cytiva)

MBS I is an excellent system for optimal microbiological control using membranes. The overall procedure time is reduced to a minimum. The design of the system, which consists of an electrical membrane dispenser, a funnel dispenser, and a vacuum manifold, leads to more reproducible results. All components are sold separately. The modular system provides flexibility to select the hardware and accessories that best suit the unique and varied workflows of the user.
The special sealing technique ensures easy handling and high integrity of the funnel and membrane during filtration. This keeps any cross-contamination to a minimum.

Supplier: ANTIBODIES.COM

Mouse TGF beta Receptor I ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse TGF beta Receptor I in serum, plasma, and other biological fluids.

Supplier: ProSci Inc.

ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha ) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha , notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha , notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.

Supplier: Hach

Convenient portable testers with replaceable sensors for measuring conductivity, TDS, salinity, temperature and pH values (only Multi 2). Backed up with built in performance diagnostics, users never have to guess when to clean or calibrate the sensor.

Supplier: Thermo Fisher Scientific

Thermo Scientific EZ-Link Sulfo-NHS-LC-Biotin is an intermediate-length, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.

Supplier: ProSci Inc.

Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CAM K II). Both PKA and CAM K II phosphorylate Ser58 which lies within the regulatory domain of TPH.

Supplier: Thermo Orion

ROSS pH electrodes offer unmatched benefits that users will not find in any other pH electrode. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: Binder

The MFK series of dynamic climate chambers has been specially developed as precision heating and cooling chambers for complex standards-based climatic testing. The units are ideal for rapid temperature changes with humidity control with a low temperature range down to –70 °C and have a higher capacity which exceeds the capability of normal testing chambers. The stainless steel inner chamber has door heating, a heated viewing window with LED interior lighting and programmable condensation protection for the test materials.

Supplier: MP Biomedicals

Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolised in the tricarboxylic acid cycle to produce carbon dioxide, water and energy.

Supplier: Thermo Fisher Scientific

The Thermo Scientific™ IntelliStack™ CO₂ Incubator shaker is a versatile laboratory instrument used for incubating and agitating samples simultaneously. It combines the functions of an incubator and shaker, providing a controlled environment for cell culture, microbial growth, and various other applications. With adjustable temperature, speed, and CO₂ concentration settings, it offers precise control over experimental conditions. A large, easy-to-use 10" colour touchscreen display with alarms, alerts, real-time monitoring of key parameters, and data logging with export via USB or Ethernet allows for easy operation.

Supplier: Ahlstrom-Munksjö

General purpose Filter Paper, N3 m/N, 90 mm, discs 1 * 100 items

Supplier: GILSON

TRACKMAN® Connected is a tablet with exclusive accessories and applications that make pipetting on 96- and 384-well plates faster and more reliable, improving your efficiency at the bench by tracking your pipetting tasks.

Supplier: Thermo Orion

Thermo Scientific™ Orion™ AquaMate UV-Vis spectrophotometers include over 260 preprogramed methods, and are designed to meet the needs of water and wastewater analysis laboratories. AquaMate UV-Vis and Visible-only spectrophotometers incorporate advanced features and functions for ultimate flexibility in operation.

Supplier: Lovibond Tintometer

A series of spectrophotometric colorimeters for colour grading of optically clear samples. Each version of the PFXi 195 includes a selection of standard colour scales that is used in a specific industry sector. Additional scales can be added, at the time of order or remotely, as optional upgrades, to provide the flexibility to meet individual requirements. Results can also be displayed in terms of spectral data and CIE values. For product types that are incompatible with the standard colour scales, the PFXi 195 software allows the users to build up a customised scale from a series of reference samples, and then to obtain the closest match to the stored reference.

Supplier: Whatman products (Cytiva)

903 sample collection card with four sample spots.

Supplier: DWK Life Sciences

The WHEATON® OmniSpence® ELITE and UniSpense® PRO are intelligent peristaltic pumps for all dispensing needs. Whether the user is making sterile liquid transfers to and from containers or filling vials or titer plates these pumps will simplify and accelerate the laboratory throughput. It is ideal for any laboratory or clinical setting where accurate and precise liquid dispensing is important.

Supplier: 3M Food Safety

The Clean-Trace™ luminometer is a simple, quick and reliable handheld diagnostic tool to verify cleaning effectiveness and capture, store and manage data for later analysis. This Hygiene Monitoring and Management System offers food safety professionals a complete system of products consisting of a luminometer handheld device, compatible tests and a powerful new software platform, to verify that surfaces have been effectively cleaned in seconds, for better decision making and audit preparedness.

Supplier: OHAUS

These digital dry block heaters with heated lid are designed for applications that require repeatable results and superior temperature stability. These multi-purpose units are ideal for isothermal incubation, enzyme reactions, immunoassays, nucleic acid denaturation and a wide variety of other laboratory procedures.

Supplier: SIOEN

This waterproof and windproof jacket is made of anti-static Siopor® FR AST fabric: 100% polyester fabric with 100% FR PU coating + AST. It features a fixed flame-retardant cotton lining with two inside pockets. The outer fabric is water-repellent, while the coating on the inside attracts moisture and keeps the skin dry.

Supplier: MEMMERT

Sets eco standards for cultivation below room temperature: Unmatched energy efficiency, excellent heat-up, cool-down and recovery times.

Supplier: AGILENT

The original QuikChange Site-Directed Mutagenesis Kits speed up and simplify site-directed mutagenesis studies. The kits eliminate the need for sub-cloning into M13-based bacteriophage vectors and for ss-DNA rescue. This allows oligo-mediated introduction of site-specific mutations into virtually any double-stranded plasmid DNA. In addition, the XL version of the kit is specially designed for efficient mutagenesis of large (4 to 14 kb) or otherwise difficult-to mutagenise plasmid templates. The XL kit features components specifically designed for more efficient DNA replication and bacterial transformation.

Supplier: Merck

Milli-Q® EQ 7008/7016 ultrapure and reverse osmosis (RO, Type 3) water systems are designed to produce consistent ultrapure water quality [resistivity 18,2 MΩ.cm at 25 °C; total organic carbon (TOC) ≤5 ppb] direct from a tap water source. Final ultrapure water quality can be adapted to each user’s specific application requirements. Plus, a range of intelligent design features make it effortless to dispense water as needed and where needed in the lab.