136897 Results for: "5-Chloro-2-methylpyrimidine-4-carboxylic+acid"

Supplier: Antibodies.com

Human CaMKII alpha ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human CaMKII alpha in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rat PGC1 alpha ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat PGC1 alpha in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Chicken beta Nerve Growth Factor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of chicken beta Nerve Growth Factor in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ProSci Inc.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.

Supplier: ProSci Inc.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Supplier: Biosensis

p75NTR (CD271) was originally discovered as a low affinity nerve growth factor receptor (NGFR). Later it was found that it was the receptor for all neurotrophins, including NGF, BDNF, NT3 and NT4/5. It mediates signals of neurotrophins for neuronal survival, apoptosis, neurite outgrowth and synaptic plasticity. Recently, it has been revealed that p75NTR not only acts as the receptor for neurotrophins but also the receptor for many other pathological ligands such as prions, rabies virus and amyloid beta. p75NTR also acts as a co-receptor for NOGO which mediates inhibitory signals of myelin associated protein. p75NTR is highly expressed in a number of non-neuronal and neuronal cells including motor neurons during development and also in damaged neurons. Recent research proposes the extracellular domain of p75NTR as a biomarker for monitoring the progression of motor neuron disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease.
This antibody reacts with human, mouse and rat. Cross-reactivity with other species not tested but expected.

Supplier: Biotium

PMA Enhancer for Gram Negative Bacteria was designed to improve PMA- and PMAxx™-mediated discrimination between live and dead gram-negative bacteria.

Supplier: Antibodies.com

Human non-muscle Myosin IIB/MYH10 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human non-muscle Myosin IIB/MYH10 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse alpha 2a Adrenergic receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse alpha 2a Adrenergic receptor in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse alpha smooth muscle Actin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse alpha smooth muscle Actin in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human HCF-1/Host Cell Factor C1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human HCF-1/Host Cell Factor C1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce SDAD (NHS-SS-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 13.5Å spacer arm containing a cleavable disulfide bond separates the two photoreactive groups.

Supplier: SARSTEDT

S-Monovette® is a blood collection system that combines two blood collection techniques – aspiration and vacuum. The S-Monovette® is suitable for all vein conditions and achieves an optimal sample quality, thereby producing the best results. The aspiration technique is a gentle technique for routine blood collection. Using the vacuum technique, a 'fresh' vacuum is always available.

Supplier: Antibodies.com

Rat NF-kB p65 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat NF-kB p65 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Biotium

One-Step Lumitein™ Protein Gel Stain is a ready-to-use luminescent red protein gel stain. It is a dramatically improved version of our original Lumitein™ protein gel stain in terms of convenience and safety. One-Step Lumitein™ can detect as little as approximately 1-10 ng of protein per band.

Supplier: ProSci Inc.

GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by Protein Kinase C modulates the interaction of GAP-43 with actin.

Supplier: TERRACYCLE

A Zero Waste Box™ is a complete and convenient solution which includes the storage, shipping and recycling of a particular type of waste that isn’t currently recycled through local councils or traditional recycling facilities.

Supplier: TERRACYCLE

A Zero Waste Box™ is a complete and convenient solution which includes the storage, shipping and recycling of a particular type of waste that isn’t currently recycled through local councils or traditional recycling facilities.

Supplier: AGILENT

BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

Supplier: KIMBERLY CLARK

WypAll® L10 centrefeed roll, designed for light-duty hygiene wiping and perfect for tasks like cleaning food preparation and service surfaces. Compatible with the portable WypAll® Reach™ dispenser (115-2528) which ensures rolls remain enclosed to help prevent against transmission of food-borne bacteria.

Supplier: Biosensis

The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration. The fluorescent dye Fluoro-Jade® B (FJB), like its more purified brother Fluoro-Jade® C (FJC), is an anionic fluorescein derivative useful for the histological staining of neurons undergoing degeneration.

Supplier: Cytiva

Amersham™ Protran® membranes are manufactured from 100% pure nitrocellulose to ensure the highest binding capacity possible. They are compatible with a variety of detection methods, including isotopic, chemiluminescent, colorimetric and fluorescent. No methanol pre-wetting step is required, making this the membrane of choice for proteins which prefer aqueous environments. Prior to transfer the membrane is simply wetted with water, and then placed in the transfer buffer. No other pretreatment steps are necessary.

Supplier: Antibodies.com

Human alpha smooth muscle Actin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human alpha smooth muscle Actin in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ProSci Inc.

AIF Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.

Supplier: Antibodies.com

Human Fc Fragment of IgA Receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Fc Fragment of IgA Receptor in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human non-muscle Myosin IIA ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human non-muscle Myosin IIA in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human ZO1 Tight Junction Protein ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human ZO1 Tight Junction Protein in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human Insulin degrading enzyme/IDE ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Insulin degrading enzyme/IDE in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rat CaMKII beta ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat CaMKII beta in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Monkey beta Nerve Growth Factor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of monkey beta Nerve Growth Factor in serum, plasma, tissue homogenates, and other biological fluids.