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23323 results for "4-(4-Fluorophenyl)tetrahydro-pyran-4-carboxylic+acid&pageNo=13"

23323 Results for: "4-(4-Fluorophenyl)tetrahydro-pyran-4-carboxylic+acid&pageNo=13"

Overalls, Fristads® PR54-820, design A, navy blue

Overalls, Fristads® PR54-820, design A, navy blue

Supplier: FRISTADS KANSAS

Work overalls made from 65% polyester and 35% cotton. With napped inner.

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HPLC/UHPLC columns, Kromasil® Classic, 100 Å

Supplier: HICHROM

The Kromasil® Classic 100 Å family of products is used to separate and purify molecules of up to 10000 Da. Drug candidates for the pharmaceutical, natural products and API industries are separated and purified using Kromasil® Classic 100 Å columns.

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Anti-THEM2 Rabbit Polyclonal Antibody

Anti-THEM2 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

THEM2 Antibody: THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

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Flame resistant light weight overalls, FR28

Flame resistant light weight overalls, FR28

Supplier: Portwest

This anti-static overall is made of the innovative flame-resistant Bizflame Plus™ fabric. Sew on flame resistant industrial wash tape.

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Corning® Nu-Serum™ Serum Replacements, Corning

Corning® Nu-Serum™ Serum Replacements, Corning

Supplier: Corning

Corning® Nu-Serum™ growth media supplement provides a low-protein alternative to newborn calf, foetal bovine, and other sera routinely used for cell culture. The low-protein content facilitates protein purification, virus production, monoclonal antibody production and screening, and increases the frequency of successful transfection of cells.

   Sustainable Options Available
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Trousers, Portwest Texo, TX11

Trousers, Portwest Texo, TX11

Supplier: Portwest

Stylish and practical work trousers made of cotton rich fabric (60% cotton, 40% polyester). The cotton ensures it washes well at 60 °C whilst the polyester gives a ruggedness essential for daily use. Can be twinned with TX10 contrast jacket.

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HPLC columns, NUCLEODUR® C18 Gravity

HPLC columns, NUCLEODUR® C18 Gravity

Supplier: MACHEREY-NAGEL

NUCLEODUR® C18 Gravity is an octadecyl modified silica phase with a high density coverage, using for HPLC.

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Flame retardant trousers, 2024 NX

Flame retardant trousers, 2024 NX

Supplier: FRISTADS KANSAS

Durable trousers made of Nomex® Comfort fabric, dope dyed. The fabric consists of 93% Meta-Aramid, 5% Para-Aramid and 2% anti-static fibres.

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Industrial overalls, Icon

Industrial overalls, Icon

Supplier: FRISTADS KANSAS

Bi-coloured overalls made of 65% polyester and 35% cotton, with contrast stitching.

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Human ABCA13 ELISA Kit

Human ABCA13 ELISA Kit

Supplier: Antibodies.com

Human ABCA13 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human ABCA13 in serum, plasma, and other biological fluids.

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Human BAP1 ELISA Kit

Human BAP1 ELISA Kit

Supplier: Antibodies.com

Human BAP1 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human BAP1 in serum, plasma, and other biological fluids.

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Anti-DUSP13 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss

Members of the protein-tyrosine phosphatase superfamilycooperate with protein kinases to regulate cell proliferation anddifferentiation. This superfamily is separated into two familiesbased on the substrate that is dephosphorylated. One family, thedual specificity phosphatases (DSPs) acts on both phosphotyrosineand phosphoserine/threonine residues. This gene encodes differentbut related DSP proteins through the use of non-overlapping openreading frames, alternate splicing, and presumed differenttranscription promoters. Expression of the distinct proteins fromthis gene has been found to be tissue specific and the proteins maybe involved in postnatal development of specific tissues. A proteinencoded by the upstream ORF was found in skeletal muscle, whereasthe encoded protein from the downstream ORF was found only intestis. In mouse, a similar pattern of expression was found.Multiple alternatively spliced transcript variants were described,but the full-length sequence of only some were determined.[provided by RefSeq, Jul 2008].

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Anti-DUSP13 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

Members of the protein-tyrosine phosphatase superfamilycooperate with protein kinases to regulate cell proliferation anddifferentiation. This superfamily is separated into two familiesbased on the substrate that is dephosphorylated. One family, thedual specificity phosphatases (DSPs) acts on both phosphotyrosineand phosphoserine/threonine residues. This gene encodes differentbut related DSP proteins through the use of non-overlapping openreading frames, alternate splicing, and presumed differenttranscription promoters. Expression of the distinct proteins fromthis gene has been found to be tissue specific and the proteins maybe involved in postnatal development of specific tissues. A proteinencoded by the upstream ORF was found in skeletal muscle, whereasthe encoded protein from the downstream ORF was found only intestis. In mouse, a similar pattern of expression was found.Multiple alternatively spliced transcript variants were described,but the full-length sequence of only some were determined.[provided by RefSeq, Jul 2008].

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Industrial label printers with Brady workstation LAB suite, BradyPrinter i7100

Industrial label printers with Brady workstation LAB suite, BradyPrinter i7100

Supplier: Brady

The BradyPrinter i7100 industrial thermal transfer bench top printer is ideal for customers requiring reliable high volume printing on lots of different materials within the aerospace, defence and mass transit, electronics, automotive, logistics, electrical, voice-datacom and lab markets.

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Freeze dryer, console, FreeZone®

Freeze dryer, console, FreeZone®

Supplier: LABCONCO

FreeZone® console freeze dryers with or without stoppering tray dryers are designed for lyophilising moderate to large loads and stoppering vials or serum bottles under vacuum. The console features a front viewing window and interior space for a vacuum and accommodation for a full size tray dryer such as the FreeZone® stoppering tray dryer pump (sold separately).

   Sustainable Options Available
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Filter Funnel, Conical with Fused Filter and Standard Joint NSK 10/19, 14/23 or 19/16

Filter Funnel, Conical with Fused Filter and Standard Joint NSK 10/19, 14/23 or 19/16

Supplier: ROBU GLASFILTER

ROBU® conical filter funnel with fused VitraPOR® filter and standard joint NSK 10/19, 14/23 or 19/16 ensures efficient, secure filtration in laboratory applications, combining chemical resistance with precise pore structure.

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Anti-FAM13C Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss

FAM13C1, also known as FAM13C, is a 585 amino acid protein that belongs to the FAM13 family. Existing as three alternatively spliced isoforms, the gene encoding FAM13C1 maps to human chromosome 10, which contains over 800 genes, 135 million nucleotides and makes up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

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Anti-FAM13C Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

FAM13C1, also known as FAM13C, is a 585 amino acid protein that belongs to the FAM13 family. Existing as three alternatively spliced isoforms, the gene encoding FAM13C1 maps to human chromosome 10, which contains over 800 genes, 135 million nucleotides and makes up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

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Megafuge® 8/8R Centrifuges, Bench Top, Ventilated/Refrigerated

Megafuge® 8/8R Centrifuges, Bench Top, Ventilated/Refrigerated

Supplier: Thermo Scientific

These durable centrifuges are available as ventilated or refrigerated versions and provide exceptional capacity in a compact design with a smart, simple interface.

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Fluorescent nerve terminal probes and stains

Fluorescent nerve terminal probes and stains

Supplier: Biotium

Nerve terminal probes are a series of fluorescent cationic styryl dyes developed to follow synaptic activity. These dyes have a lipophilic tail at one end and a hydrophilic cationically charged head group at the other end. The dyes vary in the number of carbons in the lipophilic tail (m) and the number of double bonds linking the two aromatic rings in the dye (n). AM dyes are similar to FM dyes, but contain an additional formaldehyde-fixable amino group in the cationic head.

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Anti-SLC6A13 Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.

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Balance enclosures, XPert™

Balance enclosures, XPert™

Supplier: LABCONCO

XPert™ balance enclosures provide user protection by keeping powders, particulates and fume contained during weighing procedures. They are well suited for pharmaceutical research and other laboratory applications involving weighing of toxic substances. These vented balance safety enclosures may be ducted to the outside or connected to the FilterMate Portable Exhauster to be exhausted back into the laboratory through HEPA filters, carbon filters, or a combination of both HEPA and carbon filters.

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Sleeve protector, cut resistant, HyFlex® 11-200

Sleeve protector, cut resistant, HyFlex® 11-200

Supplier: Ansell

This high visibility sleeve with Level 5 cut performance and Level 1 thermal protection is knitted from polyester, nylon and glass fibres. The anatomic design with adjustable forearm area enables freedom of movement so workers can do the job without constraints, increasing productivity.

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Anti-PTPN13 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

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Anti-PTPN13 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

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Anti-SOX13 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

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Accessories for vortex mixers Vortex-Genie®

Accessories for vortex mixers Vortex-Genie®

Supplier: SCIENTIFIC INDUSTRIES ELMIS

* Multiple sample starter set consists of a 152 mm platform, a foam insert for 60 microtubes and a foam insert for one standard microplate
** Large sample set is ideal for mixing beakers, flasks and large tubes. The set consists of a recessed platform, two elastic bands, a blank foam insert, a foam insert for 4×29 to 37 mm tubes, a foam insert for 8×14 to 29 mm tubes and a foam insert for 12×9 to 16 mm tubes
*** Small ampoule/tube attachment enables vigorous end-to-end mixing for up to four 15 to 17 mm Ø tubes or ampoules
**** Large ampoule/tube attachment enables vigorous end-to-end mixing for up to four 10 to 17 mm Ø tubes or ampoules.

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Bio process sterilisable pH and ORP electrodes, SteamLine

Bio process sterilisable pH and ORP electrodes, SteamLine

Supplier: SI Analytics

Autoclavable high-tech electrodes with outstanding electrical and physical performance characteristics guaranteeing exceptional accuracy and reliability over long periods of time. Can be used in demanding environments such as SIP treatment (Sterilisation in Place), and CIP cleaning (Clean in Place).

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Cryogenic vials, TruCool®

Cryogenic vials, TruCool®

Supplier: BIOCISION

TruCool® leak-proof cryogenic vials feature a screw cap with a thermally-fused gasket to ensure a tight seal. The gasket is a co-molded thermoplastic elastomer (TPE) layer, which prevents leaking, slipping and risk of contamination. The gasket is 95 kPa certified to provide a leak-proof seal. These vials are sterile and individually barcoded with a unique identifier which can be read with common barcode readers. Ideal for use in CoolRack® CF cryogenic vial modules and CoolCell® alcohol-free cell freezing containers. Recommended for use in vapor phase LN₂ only.

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HPLC columns, PLRP-S

HPLC columns, PLRP-S

Supplier: VARIAN

The PLRP-S family of products consists of a range of pore sizes and particle sizes, all with identical chemistry and fundamental adsorptive characteristics. The particles are inherently hydrophobic so there is no bonded phase, alkyl ligand required for reversed-phase separations. This gives a highly reproducible material that is free from silanols and heavy metal ions. Within the extensive product range are columns suitable for analytical separations and preparative purifications.

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