23386 Results for: "4-(4-Fluorophenyl)tetrahydro-pyran-4-carboxylic+acid&pageNo=13"

Supplier: Bioss

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].

Supplier: ALSICO

Multirisk trousers especially designed for APC 2.

Supplier: Bioss

Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).

Supplier: Bioss

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Supplier: BELLINGHAM STANLEY

Polarimeter tube, PEEK end, centre fill, glass, central arm, for HCl - 200mm 1 * 1 items

Supplier: Avantor Fluid Handling

5/16 X 1/2 PT TBNG 1 * 25 items

Supplier: Cole Parmer

RING SIZE 18 7MM HOLE 1 * 1 items

Supplier: Avantor Fluid Handling

TBG PLAT SIL1-1/4X1-3/4 25'/7.62M 1 * 25 Feet

Supplier: Avantor Fluid Handling

FTNG S B 5/32X3/16 PVDF 1 * 1 items

Supplier: Avantor Fluid Handling

VITON 6'' SANITARY GASKET CLAMP RINGS 1 * 1 items

Supplier: Cole Parmer

control bearing housing assembly 1 * 1 items

Supplier: Avantor

Suitable for use on Tecan Freedom EVO or Tecan Fluent. Available in conductive and non conductive versions, with or without filter, and in CE-IVD marked version for clinical diagnostic applications.

Supplier: DuPont

These Tyvek® overalls are made from flash spun, high density polyethylene, providing an ideal balance of protection, durability and comfort. Tyvek® is permeable to both air and water vapour, yet repels water-based liquids and aerosols. It offers an excellent barrier against fine particles and fibres (down to 1 micron in size).

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: Bioss

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Supplier: Bioss

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].

Supplier: Portwest

Stylish and practical work trousers made of cotton rich fabric (60% cotton, 40% polyester). The cotton ensures it washes well at 60 °C whilst the polyester gives a ruggedness essential for daily use. Can be twinned with TX10 contrast jacket.

Supplier: HICHROM

The Kromasil® Classic 100 Å family of products is used to separate and purify molecules of up to 10000 Da. Drug candidates for the pharmaceutical, natural products and API industries are separated and purified using Kromasil® Classic 100 Å columns.

Supplier: ProSci Inc.

THEM2 Antibody: THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

Supplier: Portwest

This anti-static overall is made of the innovative flame-resistant Bizflame Plus™ fabric. Sew on flame resistant industrial wash tape.

Supplier: COLLECTION PREFIX HPLC

PC equipment optimised for use with laboratory devices and software. Designed to meet laboratory conditions, ensuring necessary performance. Includes a wide range of accessories such as monitors and keyboards.

Supplier: Corning

Corning® Nu-Serum™ growth media supplement provides a low-protein alternative to newborn calf, foetal bovine, and other sera routinely used for cell culture. The low-protein content facilitates protein purification, virus production, monoclonal antibody production and screening, and increases the frequency of successful transfection of cells.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C18 Gravity is an octadecyl modified silica phase with a high density coverage, using for HPLC.

Supplier: FRISTADS KANSAS

Work overalls made from 65% polyester and 35% cotton. With napped inner.

Supplier: Antibodies.com

Human BAP1 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human BAP1 in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Human Kisspeptin ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Kisspeptin in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Human ABCA13 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human ABCA13 in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Human H Cadherin ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human H Cadherin in serum, plasma, and other biological fluids.

Supplier: FRISTADS KANSAS

Durable trousers made of Nomex® Comfort fabric, dope dyed. The fabric consists of 93% Meta-Aramid, 5% Para-Aramid and 2% anti-static fibres.