10713 Results for: "3-(Trifluoromethyl)quinoxaline-2-carboxylic+acid&pageNo=19&view=easy"

Supplier: Biosensis

Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) due to its molecular mass and its ability to bind at low affinity not only NGF (see 162030), but also other neurotrophins, including brain-derived neurotrophic factor (BDNF; 113505), neurotrophin-3 (NTF3; 162660), and neurotrophin-4/5 (NTF5; 162662). At the time of its discovery, NGFR was considered a unique type of protein. Subsequently, however, a large superfamily of tumor necrosis factor receptors were found to share the overall structure of NGFR (4 extracellular ligand-binding, cysteine-rich repeats, or CRs, and signaling through association with, or disassociation from, cytoplasmic interactors). The identification of this superfamily helped elucidate some of the biologic functions of NGFR, including its ultimate involvement in the nuclear factor kappa-B (NFKB; see 164011) and apoptosis pathways. As a monomer, NGFR binds NGF with low affinity. Higher affinity binding is achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1; 191315), TRKB (NTRK2; 600456), and TRKC (NTRK3; 191316). TRKA, TRKB, and TRKC are specific for or 'preferred by' NGF, NTF5 and BDNF, and NTF3, respectively (Ip et al., 1993). NTF3 also binds to TRKA and TRKB, but with significantly lower affinity

Supplier: AGILENT

XL1 and XL2-Blue Competent Cells are versatile for routine cloning and allow blue-white colour screening for high efficiency cloning of methylated DNA.

Supplier: DWK Life Sciences

POTTER ELVEHJEM SIZE19 1ML ALL-GLASS 1 * 1 items

Supplier: ProSci Inc.

Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Lys63-linked Ubiquitin chain formation. More specifically, UBE2V1 orients the Ubiquitin molecule to favor linkage at Lys63 via a non-covalent interaction with the Ubiquitin molecule. The UBE2V1-UBE2N heterodimer catalyses the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. UBE2V1 plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human STAT1 (alpha). 1 * 100 µG

Supplier: Rmoni

Rmoni offers complete end-2-end sensor solutions to set up an Environmental Monitoring Solutions (EMS) in hospitals, laboratories, pharmacies and cleanrooms. Keeping track of all critical parameters including temperature, humidity and many more. Ensuring product and process integrity during storage, handling and as well as transportation.

Supplier: Dräger

The powered air-purifying respirator (PAPR) X-plore 8000 offers a number of user friendly standard and specialised carrying systems for standard and decontamination applications. Dräger has also developed a wide range of tight- and loose-fitting headgear such as half and full-face masks, short and long hoods and helmets with visor and protective visor. Standard and enhanced flexibility hoses are available and compatibility is ensured. Modular components: A wide range of components for every application.

Supplier: MACHEREY-NAGEL

The high purity CHROMABOND® adsorbents can be used for a self-filling of SPE columns or further analytical applications.

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SIRT1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SMAD2. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic phosphopeptide of human STAT5A. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SOX10. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SDHB. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SAA1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SMC1A. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SOD2. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SMARCB1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human STAT1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human S100A9. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human S100P. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SMAD1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SMAD2. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SP1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SFRP1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SOS1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SIRT5. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human SHH. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human STIM1. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic peptide of human STAT5A. 1 * 100 µG

Supplier: Abnova

Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SMAD5. 1 * 100 µG