Procaspase-3-activator (PAC-1) ≥98% (by HPLC), white to off-white solid
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Caspase-3 activator
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DIPPMPO ≥98% (by TLC, 1H-NMR, 13C-NMR)
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Most efficient spin trap for the in vitro and in vivo detection of O-, N-, S-, and C-centered free radicals.
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DAF-FM diacetate 2,5 mg/ml ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Fluorescent probe for NO detection. Cell permeable.
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DAF-2 diacetate 5 mM in DMSO ≥98% (by HPLC)
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Fluorescent probe for NO detection. Cell permeable.
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6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt, disodium salt ≥98% (by TLC)
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AMPA/kainate receptor antagonist
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5-(N-Ethyl-N-isopropyl)amiloride ≥98% (by TLC)
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Selective inhibitor of the Na /H antiporter.
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3,5-Dimethyl-1-adamantanamine hydrochloride ≥98% (by argentometric titration)
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NMDA receptor antagonist.
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Dimethyl-W84 dibromide ≥98% (by HPLC)
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M2 receptor modulator.
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PNU-120596 ≥98% (by HPLC)
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Nicotinic acetylcholine receptor activator.
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5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid ≥95% (by HPLC)
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R527 ligand.
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Benzamil hydrochloride ≥98% (by HPLC), yellow solid
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Na⁺ channel blocker
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PROTEASOME 19S RPN10/S5A SUBUNIT MONOCLONAL ANTIBODY (S5A-18) 1 * 100 µl
Supplier: ENZO LIFE SCIENCES
PROTEASOME 19S RPN10/S5A SUBUNIT MONOCLONAL ANTIBODY (S5A-18) 1 * 100 µl
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RK-682 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
RK-682 is a novel tyrosine phosphatase inhibitor isolated from Streptomyces sp. It inhibits the dual specificity VHR phosphatase (IC50=2.0µM) selectively over CD45 (IC50=54µM), Cdc25B and PTP1B (IC50~42µM). RK-682 inhibits cell cycle progression of Ball-1 cells at the G1/S transition and enhances ATP-induced long-term potentiation in guinea pig hippocampal CA1 neurons. Shows potent activity against HIV-1 protease.
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Anti-Proteasome 20S beta5t subunit Mouse Monoclonal Antibody [clone: b8-17]
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Anti-Proteasome 20S beta5t subunit Mouse Monoclonal Antibody [clone: b8-17]
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L-α-Phosphatidylinositol-3,4,5-P3 ·7Na ≥98% (by TLC)
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PKC substrate.
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U-46619 ≥98%
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Prostaglandin H₂/thromboxane A₂ receptor agonist; stable analog of thromboxane A₂. Induces platelet aggregation at 32 nM and activates p38 MAPK.
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N,N-Dimethylsphingosine, D-erythro ≥98% (by TLC)
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Sphingosine kinase inhibitor
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N-Hexanoyl-D-erythro-sphingosine ≥98% (by TLC)
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A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.
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Anti-Bcl-2 Mouse Monoclonal Antibody [clone: 83-8B]
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The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains.
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Nω-Nitro-L-arginine methyl ester hydrochloride ≥98% (by TLC)
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Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine. Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA.
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L-Theanine ≥98% (by titrimetric analysis)
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Glutamate receptor ligand.
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N-Methyl-D-aspartic acid ≥98% (by TLC)
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NMDA receptor agonist.
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Z-Asp-2,6-dichlorobenzoyloxymethylketone ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Caspase inhibitor