131680 Results for: "2-Fluoro-4-methyl-3-(trifluoromethyl)benzyl+bromide&pageNo=14"

Interleukin-1 beta (IL-1β) is also known as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1 beta.
IL1β are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1α and IL1β are regulated independently, they bind to the same receptor and exert identical biological effects.
IL-1β is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

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Mouse Recombinant IL-10 (from E. coli)

Supplier: Shenandoah Biotechnology

Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ƴ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Mouse IL-10 is not active on human cells.

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ReadyTube™12 MSRV Medium ISO 6579

Supplier: MERCK LIFE SCIENCE

ReadyTube™12 MSRV Medium ISO 6579

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Mouse Recombinant IL-11 (from E. coli)

Supplier: Shenandoah Biotechnology

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling.

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Human Recombinant IL-13 (from E. coli)

Supplier: Shenandoah Biotechnology

Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive.

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Human CTRP6 peptide (15 aa in the center)

Supplier: ProSci Inc.

CTRP6 peptide is used for blocking the activity of CTRP6 antibody.

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Human TLR6 peptide (13 aa in the center)

Supplier: ProSci Inc.

TLR6 peptide is used for blocking the activity of TLR6 antibody.

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Human BAP29 peptide (17 aa in the center)

Supplier: ProSci Inc.

BAP29 peptide is used for blocking the activity of BAP29 antibody.

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Human SAPAP4 peptide (13 aa in the center)

Supplier: ProSci Inc.

SAPAP4 peptide is used for blocking the activity of SAPAP4 antibody.

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Anti-ITGB2 Recombinant Antibody [Clone: 1B4]

Supplier: ProSci Inc.

Anti-ITGB2 Recombinant Antibody [Clone: 1B4]

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Anti-Cytokeratin 8+18 Rabbit Polyclonal Antibody

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to Cytokeratin 8 for WB and ELISA with samples derived from Human and Mouse.

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Human IL-12 p70 ELISA Kit

Supplier: ANTIBODIES.COM

Human IL-12 p70 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL-12 p70 in serum, plasma, tissue homogenates, and other biological fluids.