94174 Results for: "2-Amino-4-methylpyrimidine-5-carboxylic+acid&pageNo=9"

Cell permeable inhibitor human (IC50=4µM), fission yeast (IC50=5µM), S. cerevisiae (IC50=12µM) and bovine (IC50=17µM) Arp2/3 complex between Arp2 and Arp3. Inhibits Listeria motility (IC50=7µM).

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SMI-4a ≥95%

Supplier: Enzo Life Sciences

Pim1 inhibitor

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Fenofibrate ≥98% (by HPLC)

Supplier: Enzo Life Sciences

PPARα activator.

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SB 225002 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Chemokine receptor ligand

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TCS JNK 5a ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Thienylnaphthamide compound. Potent inhibitor of JNK2 (pIC50=6.5) and JNK3 (pIC50=6.7) targeting the ATP-binding site. Has no activity against JNK1.

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Sulindac Sulphide ≥99% (by TLC)

Supplier: Enzo Life Sciences

Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.

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ICI-118,551 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Adrenergic receptor ligand.

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N-(6-Aminohexyl)-5-chloro-1-naphthalenesulphonamide hydrochloride ≥98% (by TLC)

Supplier: Enzo Life Sciences

Binds to calmodulin, inhibiting Ca²⁺-calmodulin-regulated enzyme activity. It inhibits the Ca²⁺/calmodulin-induced activation of myosin light chain kinase in a concentration dependent manner (IC50=25 µM). Cell permeable.

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[6]-Gingerol ≥97% (by HPLC)

Supplier: Enzo Life Sciences

ATPase activator.

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1-Methyl-9H-Pyrido[3,4-B]Indole 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

1-Methyl-9H-Pyrido[3,4-B]Indole 100mg pack 1 * 100 mg

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2,4,8,10-Tetraoxaspiro[5.5]Undecane-3,9-DiylBis(2-Methylpropane-2,1-Diyl) Bis(3-(3-(Tert-Butyl)-4-Hydroxy-5-Methylphenyl)Propanoate) 2.5kg pack 1 * 2,5 kg

Supplier: Apollo Scientific

2,4,8,10-Tetraoxaspiro[5.5]Undecane-3,9-DiylBis(2-Methylpropane-2,1-Diyl) Bis(3-(3-(Tert-Butyl)-4-Hydroxy-5-Methylphenyl)Propanoate) 2.5kg pack 1 * 2,5 kg

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2-Amino-9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-3H-Purine-6,8(7H,9H)-Dione 1g pack 1 * 1 g

Supplier: Apollo Scientific

2-Amino-9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-3H-Purine-6,8(7H,9H)-Dione 1g pack 1 * 1 g

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2'-anilino-6'-[ethyl(3-methylbutyl)amino]-3'-methylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one 25g pack 1 * 25 g

Supplier: Apollo Scientific

2'-anilino-6'-[ethyl(3-methylbutyl)amino]-3'-methylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one 25g pack 1 * 25 g

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2-Bromo-9,9-Dioctyl-9H-Fluorene 5g pack 1 * 5 g

Supplier: Apollo Scientific

2-Bromo-9,9-Dioctyl-9H-Fluorene 5g pack 1 * 5 g

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2-Bromo-6,9-Diphenylcarbazole 5g pack 1 * 5 g

Supplier: Apollo Scientific

2-Bromo-6,9-Diphenylcarbazole 5g pack 1 * 5 g

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2-Bromo-9,9-Dioctyl-9H-Fluorene 25g pack 1 * 25 g

Supplier: Apollo Scientific

2-Bromo-9,9-Dioctyl-9H-Fluorene 25g pack 1 * 25 g

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Mifepristone ≥99%

Supplier: Enzo Life Sciences

Progesterone receptor ligand.

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SC-51089 ≥98%

Supplier: Enzo Life Sciences

Prostanoid receptor inhibitor

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Mycalolide B ≥98%

Supplier: Enzo Life Sciences

Depolymerizes actin

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Parthenolide ≥97% (by TLC)

Supplier: Enzo Life Sciences

HDAC inhibitor

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N,N-Dimethylsphingosine, D-erythro ≥98% (by TLC)

Supplier: Enzo Life Sciences

Sphingosine kinase inhibitor

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N-Hexanoyl-D-erythro-sphingosine ≥98% (by TLC)

Supplier: Enzo Life Sciences

A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

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Phytoceramide C2 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Inhibits yeast growth and activates ceramide-activated protein phosphatase (CAPP).

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N-(2-Hydroxyethyl)oleamide ≥98% (by TLC)

Supplier: Enzo Life Sciences

Activates TRPV1. Endogenous anandamide-like lipid which regulates appetite but does not bind to cannabinoid receptors. In rats, food intake is inhibited by oral oleylethanolamide. Induces satiety by activation of PPARα. Inhibits ceramidase.

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Ono-RS-082 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.