93436 Results for: "2-(4-Hydroxyphenyl)ethanol&pageNo=9"
1,2-Dilauroyl-sn-glycero-3-phosphocholine ≥99% (by TLC)
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1,2-Dilauroyl-sn-glycero-3-phosphocholine ≥99% (by TLC)
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Tryptanthrin ≥98% (by 1H-NMR, HPLC)
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Inhibitor of prostaglandin and leukotriene synthesis.
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SC-236 ≥95% (by HPLC)
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Highly selective and potent inhibitor of cyclooxygenase-2 (IC50=10nM for COX-2 versus IC50=17.8µM for COX-1) with antitumor properties. Exhibits longer half-life time and reduced gastric toxicity in fasting rat model. Has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. Potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.
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Anacardic acid ≥95% (by 1H-NMR)
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Anacardic acid ≥95% (by 1H-NMR)
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1,1-Dimethylbiguanide hydrochloride ≥97%
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Antidiabetic agent
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EX 527 ≥95%
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Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).
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BAY 61-3606 hydrochloride ≥98% (by HPLC)
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Syk inhibitor
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Cylindrospermopsin ≥95% (by HPLC)
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Protein synthesis inhibitor
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Butein ≥98% (by HPLC)
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Tyrosine kinase inhibitor
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Isoxanthohumol ≥98% (by 1H-NMR)
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Phytoestrogen.
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Gramicidin A (from Bacillus brevis) ≥90% (by HPLC)
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Ionophore antibiotic.
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HC-030031 ≥98% (by HPLC)
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A potent and selective TRPA1 inhibitor.
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Bongkrekic acid triammonium salt ≥92% (by HPLC)
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Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase. It inhibits mitochondrial permeability transition pore opening. At 50 µM it inhibits dexamethasone- apoptosis in thymocytes, preventing the PARP cleavage and DEVDase (caspase-3 like) activity normally produced by these treatments.
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Fluphenazine-N-2-chloroethane 2HCl ≥98%
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A potent irreversible inactivator of calmodulin. Possesses potent antiproliferative and cytotoxic activity. It is also an irreversible D2 dopamine receptor antagonist.
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7,7-Dimethyleicosadienoic acid ≥99%
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Phospholipase inhibitor
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Tyrphostin A25 ≥99%
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A potent inhibitor of EGF receptor kinase activity (IC50=3 µM).
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H-7 dihydrochloride ≥98% (by TLC)
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Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
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Dexamethasone ≥99% (by TLC)
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Glucocorticoid receptor ligand
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D-erythro-Sphingosine ≥98% (by TLC)
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Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.
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3-Azaspiro[5.5]undecane hydrochloride ≥97% (by HPLC)
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A novel member of the spiro-piperidine class of M2 proton channel inhibitors similar to BL-1743. Displays increased potency (IC50=0.92µM) compared with amantadine.
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CP-55,940 ≥98% (by HPLC)
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Cannabinoid receptor ligand.
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Furoxan ≥99% (by HPLC)
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A novel NO donor which only releases NO in the presence of thiols. It is a potent vasodilator and inhibitor of platelet aggregation.