94174 Results for: "2,2-Difluoroethyl+trifluoromethanesulphonate&pageNo=9"

Supplier: Enzo Life Sciences

Produced in E.coli.

Supplier: Enzo Life Sciences

Phospholipase inhibitor

Supplier: Enzo Life Sciences

AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).

Supplier: Enzo Life Sciences

Propranolol blocks PLD derived DAG formation by inhibiting phosphatidate phosphohydrolase (IC50=70 µM). It is a useful tool to discriminate between PLC or PLD mediated DAG production. It is also a β-adrenergic receptor blocking agent.

Supplier: Enzo Life Sciences

IM-12 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

CORONAVIRUS (COVID-19 AND SARS-COV NP) MONOCLONAL ANTIBODY 1 * 1 mg

Supplier: Enzo Life Sciences

The FLUOR DE LYS®-Succinyl green, desuccinylase substrate offers a highly sensitive and convenient alternative to radiolabeled, succinylated histones or peptide/HPLC methods for the assay of desuccinylases such as SIRT5.

Supplier: Enzo Life Sciences

HDAC inhibitor developed at Enzo Life Sciences. Inhibits HDAC activity in HeLa nuclear extracts (IC50=5-10µM).

Supplier: Enzo Life Sciences

Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Suppresses self-renewal of embryonic stem cells.

Supplier: Enzo Life Sciences

HDAC inhibitor

Supplier: Enzo Life Sciences

PKC substrate

Supplier: Enzo Life Sciences

A major urinary metabolite of fentanyl.

Supplier: Enzo Life Sciences

Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM).

Supplier: Enzo Life Sciences

Biosynthesis via 15-OH prostaglandin dehydrogenase from lung and liver microsomes and by a nonenzymatic process.

Supplier: Enzo Life Sciences

An active but short-lived metabolite of triazolam.

Supplier: Enzo Life Sciences

Substrate for LTA₄ hydrolase and LTC₄ synthase.

Supplier: Enzo Life Sciences

LPA receptor ligand

Supplier: Enzo Life Sciences

Prostanoid receptor ligand.

Supplier: Enzo Life Sciences

Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.

Supplier: Enzo Life Sciences

PROTEASOME 19S RPN12/S14 SUBUNIT (HUMAN) MONOCLONAL ANTIBODY (P31-27) 1 * 100 µl

Supplier: Enzo Life Sciences

PROTEASOME 19S RPT5/S6A SUBUNIT MONOCLONAL ANTIBODY (TBP1-19) 1 * 100 µl

Supplier: Enzo Life Sciences

PROTEASOME 19S RPT2/S4 SUBUNIT (YEAST) POLYCLONAL ANTIBODY 1 * 25 µl

Supplier: Enzo Life Sciences

PROTEASOME 19S RPT3/S6B SUBUNIT MONOCLONAL ANTIBODY (TBP7-27) 1 * 25 µl

Supplier: Enzo Life Sciences

PROTEASOME 19S RPT4/S10B SUBUNIT MONOCLONAL ANTIBODY (P42-23) 1 * 25 µl

Supplier: Enzo Life Sciences

PP2A inhibitor

Supplier: Enzo Life Sciences

Biosynthesis via hydrolysis of prostacyclin. A reliable parameter for measurement of prostacyclin. Ultra-pure.

Supplier: Enzo Life Sciences

Prostanoid receptor ligand.

Supplier: Enzo Life Sciences

Biosynthesis via liver and renal cytochrome P-450. Induces glucagon release from pancreatic islets. Vasodilator in intestinal microcirculation. Inhibits Na+K+-ATPase. Urinary excretion in humans is increased during pregnancy-induced hypertension.

Supplier: Enzo Life Sciences

Lipoxygenase inhibitor

Supplier: Enzo Life Sciences

A potent and specific substrate analog PLA2 inhibitor (IC50=6.2 µM-porcine pancreatic PLA2). It inhibits human recombinant sPLA2 (IC50=13.7 µM) selectively over cPLA2. At 1 µM it completely blocked the myogenic response in perfused dog renal arcuate arteries.