94174 Results for: "2,2-Difluoroethyl+trifluoromethanesulphonate&pageNo=9"

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4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione ≥95% (by TLC)

Supplier: Enzo Life Sciences

Novel inhibitor of ubiquitin C-terminal hydrolase L3 (IC50 = 0.6µM). Displays 125-fold greater selectivity over UCH-L1 (IC50 = 75µM).

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Ko143 ≥96% (by HPLC)

Supplier: Enzo Life Sciences

Analog of the fungal toxin fumitremorgin C. Potent and selective inhibitor of the breast cancer resistance protein multidrug transporter (BCRP, EC90=26nM). Highly effective for increasing the intracellular drug accumulation and reversing BCRP-mediated multidrug resistance yet has little activity against P-glycoprotein, multidrug resistance-associated protein (MRP1) and other known drug transporters. In mouse models Ko143 was able to restore the intracellular accumulation and abolish the directionality in net flux of dasatinib. It is a highly useful tool for the identification of drug transport processes in complex experimental systems.

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5,8,11,14-Eicosatetraynoic acid ≥98%

Supplier: Enzo Life Sciences

Arachidonic acid uptake inhibitor

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Chaetomellic acid A ≥98% (by TLC)

Supplier: Enzo Life Sciences

Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).

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Lovastatin ≥98% (by TLC)

Supplier: Enzo Life Sciences

HMG-CoA reductase inhibitor

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NSC 23766 ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Cell-permeable, reversible, and selective Rac1 inhibitor.

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ELISA KIT HUMAN TETANUS TOXOID IGG 1 * 96 Tests

Supplier: Enzo Life Sciences

ELISA KIT HUMAN TETANUS TOXOID IGG 1 * 96 Tests

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Vented Millex® GS Syringe Filter

Supplier: Merck

Vented Millex®-GS filter units are syringe filters for sterilisation of low volume aqueous solutions where venting is desired.

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8-(4-Chlorophenylthio)-2'-O-methyladenosine-3’,5’-cyclic monophosphate sodium salt ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Specific, potent and membrane permeant activator of the Epac cAMP receptor.

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Adenosine-3',5'-cyclic monophosphate sodium salt ≥98% (by HPLC)

Supplier: Enzo Life Sciences

PKA activator.

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Podophyllotoxin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Topoisomerase inhibitor

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Ochratoxin A ≥98% (by HPLC, TLC)

Supplier: Enzo Life Sciences

Mycotoxin. Nephrotoxic.

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Stachybotrylactam (from Stachybotrys sp. MST-FP1752) ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Mycotoxin. Immunosuppressive. Weakly inhibits HIV-1 protease.

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Sterigmatocystin ≥98% (by HPLC, TLC)

Supplier: Enzo Life Sciences

Mycotoxin

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Capsazepine ≥98%

Supplier: Enzo Life Sciences

Capsaicin antagonist

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Nifedipine ≥98%

Supplier: Enzo Life Sciences

Ca²⁺ channel inhibitor

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R-(+)-DIOA ≥98%

Supplier: Enzo Life Sciences

K⁺ channel blocker

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Praziquantel ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Antihelmintic agent.

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Ruthenium(III) chloride oxide ≥90% (metals basis)

Supplier: Enzo Life Sciences

Blocks TRPV1. Capsaicin and calcium antagonist. Inhibitor of Ca²⁺/Mg2⁺-ATPase.

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Nicardipine hydrochloride ≥98%

Supplier: Enzo Life Sciences

Ca²⁺ channel inhibitor

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Tanshinone IIA ≥98% (by TLC)

Supplier: Enzo Life Sciences

AP-1 inhibitor

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15(S)-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid (HETE) ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Biosynthesis in human neutrophils, eosinophils and reticulocytes. Most abundant eicosanoid in human bronchi. Regulates T lymphocyte mitogenesis. Induces immunosupression. Stimulates migration of capillary endothelial cells and neovascularisation.

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Chaetocin ≥98% (by TLC)

Supplier: Enzo Life Sciences

Methyltransferase inhibitor

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12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid 50 µg/ml in ethanol ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Biosynthesis by platelet 12-lipoxygenase. Chemotactic and chemokinetic for PMNL2 and for vascular smooth muscle cells. Antiproliferative effect on smooth muscle cells. Second messenger in angiotensin induced aldosterone production. Induces endothelial cell retraction and tumor cell adhesion.

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8(S)-Hydroxyeicosa-5Z,9E,11Z,14Z-tetraenoic acid (HETE) solution 50 µg/ml in ethanol , 99% (by HPLC)

Supplier: Enzo Life Sciences

Activator of PKC and PPARα.

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β-Lapachone ≥98%

Supplier: Enzo Life Sciences

Topoisomerase inhibitor

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(±)-10-Hydroxycamptothecin ≥97%

Supplier: Enzo Life Sciences

A DNA topoisomerase I inhibitor that induces differentiation in HL-60 cells. It induces apoptosis in human breast cancer cell lines MCF-7 and MDA-MB-468.