5248 Results for: "1,4-Benzodioxane-6-boronic+acid&pageNo=47"

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. FUNCTION: Plays an important role in the physiology of adrenergic neurons. CATALYTIC ACTIVITY: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin. COFACTOR: Fe(2+) ion. ENZYME REGULATION: Phosphorylation leads to an increase in the catalytic activity. PATHWAY: Catecholamine biosynthesis; first step. SUBUNIT: Homotetramer. PTM: In vitro, phosphorylation of Ser-19 increases the rate of Ser-40 phosphorylation, which results in enzyme opening and activation. SIMILARITY: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency as low dopamine levels are a consistent neurochemical abnormality.

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SHOE JALAS 7148 ZENIT EVO EU47/UK12 1 * 1 PAIR

Supplier: EJENDALS

SHOE JALAS 7148 ZENIT EVO EU47/UK12 1 * 1 PAIR

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SHOE JALAS 3460A LIGHT SPORT EU47/UK12 1 * 1 PAIR

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SHOE JALAS 3460A LIGHT SPORT EU47/UK12 1 * 1 PAIR

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Jalas Shoes Occupational Mens 2112 Ronald, Regular Fit, Full Grain Leather Upper, PU Outsole, Oil-resistant Outsole, anti-static pro perties, double shock absorp zones, ESD, Black 1 * 1 PAIR

Supplier: EJENDALS

Jalas Shoes Occupational Mens 2112 Ronald, Regular Fit, Full Grain Leather Upper, PU Outsole, Oil-resistant Outsole, anti-static pro perties, double shock absorp zones, ESD, Black 1 * 1 PAIR

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SHOE JALAS 3308 DRYLOCK EU47/UK12 1 * 1 PAIR

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SHOE JALAS 3308 DRYLOCK EU47/UK12 1 * 1 PAIR

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Jalas Boot Safety 1878 Offroad, Wide fit with Aluminium Toecap & Steel Midsole, PU-Coated Leather Upper, Fleece Liner, PU Pronose, N itrile Rubber Outsole, Oil-resistant outsole, water repellant, anti-static properties, ESD, double shock absorp zones 1 * 1 PAIR

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Jalas Boot Safety 1878 Offroad, Wide fit with Aluminium Toecap & Steel Midsole, PU-Coated Leather Upper, Fleece Liner, PU Pronose, N itrile Rubber Outsole, Oil-resistant outsole, water repellant, anti-static properties, ESD, double shock absorp zones 1 * 1 PAIR

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Jalas Rigger Safety 1868 King, Wide fit with Aluminium Toecap & Steel Midsole, PU-Coated Leather Upper, PU Pronose, Nitrile Rubber O utsole, Thinsulate Heat Insulation , HR Upper, Oil-resistant outsole, water repellant, anti-static properties, ESD, d 1 * 1 PAIR

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Jalas Rigger Safety 1868 King, Wide fit with Aluminium Toecap & Steel Midsole, PU-Coated Leather Upper, PU Pronose, Nitrile Rubber O utsole, Thinsulate Heat Insulation , HR Upper, Oil-resistant outsole, water repellant, anti-static properties, ESD, d 1 * 1 PAIR

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BOOT JALAS 3150 TREK GRIP EU47/UK12 1 * 1 PAIR

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BOOT JALAS 3150 TREK GRIP EU47/UK12 1 * 1 PAIR

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SANDAL JALAS 3510R RESPIRO EU47/12 1 * 1 PAIR

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SANDAL JALAS 3510R RESPIRO EU47/12 1 * 1 PAIR

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VWR®, Refrigerated Circulators

Supplier: VWR Collection

Stainless steel circulating baths with choice of Advanced Programmable or Advanced Digital temperature controller. Both are easy to navigate with large, intuitive displays and multiple communication options, including USB-A and B, RS232/485, Ethernet and external temperature probe. The reservoir drain can be accessed by removing the front panel. All models feature user-adjustable, high temperature safety cut-off points, as well as over-temperature protection. The surface is cool to the touch, even when operating at high temperatures.