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Anti-TMEM59 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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Anti-TMEM59 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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Anti-TMEM59 Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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Work overalls with bib and braces, Prostretch Crafts Bib'N'Braces (short and long sizes)

Work overalls with bib and braces, Prostretch Crafts Bib'N'Braces (short and long sizes)

Supplier: FRISTADS KANSAS

Trousers made of 65% polyester and 35% brushed cotton. The fabric has mechanical stretch, which ensures improved comfort, especially for jobs that require a lot of movement.

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Industrial jacket, Fristads® PR54-420, design A, black

Industrial jacket, Fristads® PR54-420, design A, black

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

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Masterflex L/S Drive with Easy-Load II Precision Pump Head, PCRS, 600 rpm - Delivered with Masterflex Power Cord, 230 VAC, European Plug Type-F 180 cm long 1 * 1 items

Supplier: Avantor Fluid Handling

Masterflex L/S Drive with Easy-Load II Precision Pump Head, PCRS, 600 rpm - Delivered with Masterflex Power Cord, 230 VAC, European Plug Type-F 180 cm long 1 * 1 items

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Carrier proteins

Carrier proteins

Supplier: G-Biosciences

The use of peptides for the generation of antibodies against specific peptides has become an essential tool in proteomic research. A crucial step in using peptides as antigens is their coupling to carrier proteins. Peptides are designed to be good epitopes by themselves; however they fail to elicit a strong antibody response. The reason for this is that the epitopes are able to bind to the B-cells, but are too small to contain additional motifs required to associate with class II molecules and T-cell receptors. The carrier proteins, once coupled to the peptides, provide these additional motifs and generate a strong antibody response. All three carrier proteins are also offered as activated carrier proteins, named as ActiveHOOK™.

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Masterflex L/S Drive with Easy-Load II Precision Pump Head, PCRS, 600 rpm - Delivered with Masterflex Power Cord, 230 VAC, British P lug Type-G 180 cm long 1 * 1 items

Supplier: Avantor Fluid Handling

Masterflex L/S Drive with Easy-Load II Precision Pump Head, PCRS, 600 rpm - Delivered with Masterflex Power Cord, 230 VAC, British P lug Type-G 180 cm long 1 * 1 items

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Pipette tips, Standard

Pipette tips, Standard

Supplier: Brand

These tips are manufactured under cleanroom conditions and are automatically packaged to ensure that the tips are consistently free from contamination.

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High purity qualitative filter paper

High purity qualitative filter paper

Supplier: Ahlstrom-Munksjö

These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

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Roller Kit 1 * 1 KIT

Supplier: Cole Parmer

Roller Kit 1 * 1 KIT

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VWR® Thermal Shake Touch, Thermoshaker

VWR® Thermal Shake Touch, Thermoshaker

Supplier: VWR Collection

The Thermal Shake Touch is designed for applications that require consistent, precise results. With heating and shaking capabilities, this low profile unit uses interchangeable blocks to accommodate a wide variety of tubes and microplates. The LCD touch screen enables faster setting of temperature, speed and time, which can all be viewed at once. Display features on-screen help topics with operational tips. Touch screen is compatible with rubber gloves used in laboratories.

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High purity hardened qualitative filter paper

High purity hardened qualitative filter paper

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions. High Purity hardened filter papers grades 1288 to 1291 are also produced from cellulose with an alpha content of nearly 100% resulting in an ash content of <0,1%.

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Respirators, industrial, PX5 PAPR Series

Respirators, industrial, PX5 PAPR Series

Supplier: RPB SAFETY

The RPB PX5 is a battery powered air purifying respirator fan unit which draws in contaminated air from the wearer's immediate vicinity, passing it through internal filters, and supplying the filtered air to an approved RPB loose fitting respirator head top.

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Gastight® 1700 series syringes

Gastight® 1700 series syringes

Supplier: HAMILTON BONADUZ

These syringes are the Gastight® version of the original 700 series syringes and are ideal for dispensing volumes from 1 µl up to 500 µl.

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High purity qualitative filter paper

High purity qualitative filter paper

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

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Digital orbital shaker

Digital orbital shaker

Supplier: HEATHROW

Compact digital orbital shaker which is packed full of high end design features making this laboratory shaker a versatile unit for a vast range of protocols.

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Centrifuges, bench top, refrigerated, 5910Ri (IVD-marked)

Centrifuges, bench top, refrigerated, 5910Ri (IVD-marked)

Supplier: EPPENDORF

The refrigerated benchtop centrifuge 5910 Ri stands out for its ease of use and versatility. With a range of innovative solutions in usability, documentation and user management. The centrifuge has designed to accommodate a particularly broad spectrum of applications. Cell harvests in bottles with capacities up to 1000 ml, large-scale DNA and RNA isolations as well as Ficoll® gradients for the purification of lymphocytes and monocytes are merely a few examples of the many areas of application.

    
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Anti-KRT76 Mouse Monoclonal Antibody [clone: BCCK1-1]

Supplier: ProSci Inc.

There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki].

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Gastight® 1000 series syringes

Gastight® 1000 series syringes

Supplier: HAMILTON BONADUZ

The 1000 series is a mid volume Gastight® syringe. Gastight® syringes are ideal for dispensing both liquids and gases. They have a precision machined PTFE plunger tip which creates a leak-free seal. With the tight fit, the tip essentially wipes the interior of the syringe barrel free of sample. This feature is particularly useful with heterogeneous samples as it reduces the chance that a deposit will occur and cause the plunger to freeze.

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Cubis® II High-Capacity Micro Balances

Cubis® II High-Capacity Micro Balances

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, providing choice between applications and configurations that best suit the users' needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions. The Cubis® II range of high-capacity micro balances with a maximum load between 32 and 111 g and a readability between 0,001 mg and 0,002 mg provide the ideal choice for a broad range of applications.

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Respirators, pharma decon/easy clean, PX5 PAPR Series

Respirators, pharma decon/easy clean, PX5 PAPR Series

Supplier: RPB SAFETY

The RPB PX5 is a battery powered air purifying respirator fan unit which draws in contaminated air from the wearer’s immediate vicinity, passing it through internal filters, and supplying the filtered air to an approved RPB loose fitting respirator head top.

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Orbital shakers, Solaris™ 2000 and 4000

Orbital shakers, Solaris™ 2000 and 4000

Supplier: Thermo Fisher Scientific

Solaris orbital shakers are reliable and innovative. Ruggedly built for demanding use, they combine an ergonomic design with key feature enhancements that help save time and protect your process. The triple-eccentric drive mechanism is built with proven technology to easily support heavy loads. The belt is maintenance-free and engineered to last the life of the shaker, and the shaker mechanism itself comes with a full 2 year warranty, 5 year warranty on parts and 10 years on the drive mechanism.

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Immersion thermostats, IC series

Immersion thermostats, IC series

Supplier: IKA

The IC immersion circulators have an extended temperature range for tempering fluids in open and covered water baths up to 200/250 °C. The LED/ graphic TFT Display illustrates all relevant process parameters. Units feature push and turn buttons for intuitive menu navigation. IC immersion circulators ensure short heating up times and have a temperature stability of ±0,01/0,02 K (basic/control model). Both models feature optical and acoustic safety warnings, an adjustable safety circuit, a powerful pressure/suction pump and can be used for internal and external applications.

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Bench top centrifuges and packages, Megafuge ST1 and ST1R Plus

Bench top centrifuges and packages, Megafuge ST1 and ST1R Plus

Supplier: Thermo Scientific

Thermo Scientific™ Megafuge ST1/ST1R Plus bench top centrifuges offer intuitive controls and versatility for power at every turn.

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VWR®, Cooling Thermal Shake Touch, Thermo Shakers

VWR®, Cooling Thermal Shake Touch, Thermo Shakers

Supplier: VWR Collection

The cooling thermal shake touch is designed for applications that require consistent, precise results. With heating, cooling and shaking capabilities, this low profile unit uses interchangeable blocks to accommodate a wide variety of tubes and microplates. The LCD touch screen enables faster setting of temperature, speed and time, which can all be viewed at once. Display features on-screen help topics with operational tips. Touch screen is compatible with rubber gloves used in laboratories.

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HPLC columns, Purospher® STAR RP-18 endcapped

HPLC columns, Purospher® STAR RP-18 endcapped

Supplier: Merck

Fast method development of complex samples across the pH range from 1,5 to 10,5 with different mobile phases and temperature conditions.
Purospher® STAR RP-18 endcapped HPLC columns are designed for universal use. Basic, neutral and metal-chelating compounds can easily be separated with simple mobile phases – naturally without peak tailing. Thanks to its outstanding performance and stability, Purospher® STAR RP-18 endcapped offers maximum flexibility in method development. Robust methods can be developed over the entire pH range from 1,5 to 10,5. High pH-stability allows the separation of strongly basic compounds with alkaline eluents. The combination of high purity silica, best all-round retention characteristics, outstanding pH stability up to pH 10,5, and suitability for up to 100% aqueous mobile phases, make Purospher® STAR RP-18 endcapped an all-round top performance column, almost universal in its range of applications.

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Respirators, gas filters, PX5 PAPR Series

Respirators, gas filters, PX5 PAPR Series

Supplier: RPB SAFETY

The RPB PX5 is a battery powered air purifying respirator fan unit which draws in contaminated air from the wearer's immediate vicinity, passing it through internal filters, and supplying the filtered air to an approved RPB loose fitting respirator head top.

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MSC-Advantage™ Microbiological Safety Cabinet, Class II

MSC-Advantage™ Microbiological Safety Cabinet, Class II

Supplier: Thermo Scientific

This biological safety cabinet combines smart design and extraordinary value with best in class energy efficiency, reliability and usability. The advanced design of the MSC-Advantage biological safety cabinet improves overall operation and maintenance, maximises safety and optimises service and clean-up. With advanced internal airflow and motor technology, MSC-Advantage cabinets offer optimal energy efficiency, operation and serviceability. At full speed the motors consume 60% less energy than standard cabinets. To further conserve energy, the intelligent speed control automatically reduces blower speed to 30% when the window is closed. This technology extends HEPA filter life while ensuring a sterile working environment and saves energy to minimise operating costs.

    
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Cubis® II MCA 125S Ultra-High Resolution Semi-Micro Balances

Cubis® II MCA 125S Ultra-High Resolution Semi-Micro Balances

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

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