97356 Results for: "(Triphenylphosphoranylidene)acetonitrile&pageNo=25"

Supplier: MP Biomedicals

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Other uses for poly-lysine have been reported as well:
• Conjugation to methotrexate for increased drug transport.
• Microencapsulation of islets.
• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.
• Immobilation of living cells in biocompatible semipermeable microcapsules.
• In the preparation of polycationic beads.
• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Supplier: Hach

COPPER FREE REAGENT POWDER PILLOWS 1 * 100 items

Supplier: MACHEREY-NAGEL

QUANTOFIX CHLORINE 500 TEST STRIPS 1 * 100 Tests

Supplier: IKA

Tool kit for dismantling T25 homogeniser dispersing tools,IKA 1 * 1 items

Supplier: VARIAN

TUBING SS REG 25MX1/4INCHX4.4 EA=25MR 1 * 1 items

Supplier: MERCK PRODUCTION CHEMICALS

Potassium sorbate powder, EMPROVE ESSENTIAL Ph Eur,BP,NF,FCC,E 202 1 * 1 kg

Supplier: HIRSCHMANN

Flask, volumetric, capacity 25ml, class A, USP certificate 1 * 1 items

Supplier: Cytiva

illustra™ MicroSpin™ S-400 HR columns designed for rapid purification of PCR products (>200 bp) from unincorporated primers (<32-mers) and nucleotides using spin-column chromatography.

Supplier: ProSci Inc.

FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Supplier: ProSci Inc.

Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, but it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with host cell surface proteins containing oligosaccharides with terminal sialyl residues. Its extracellular region has two domains (HA1 and HA2); HA1 is cleaved from the main hemagglutinin protein by the host immune system. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. This more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the efficiency of this type of transmission is low. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.

Supplier: Hospidex

Microsyringe 25µl GC standard with glass handle and fixed needle 1 * 1 items

Supplier: HIRSCHMANN

VOL.FLASK 25ML NS10/19 A HOLLOW GLASS 1 * 2 items

Supplier: Thermo Fisher Scientific

The Pierce™ yeast DNA extraction reagent kit uses Y-PER yeast protein extraction reagent to quickly extract and purify genomic and plasmid DNA from yeast.

Supplier: MP Biomedicals

Dimethyl Sulfoxide is ideal for use as a cryoprotectant. Also used in chemical reactions, in polymerase chain reactions (PCR) as a PCR cosolvent to help improve yields, especially in long PCR, and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal-induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines, embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). Used to enhance dermal absorption of many chemicals. A solvent for many organic and inorganic compounds including fats, carbohydrates, dyes, resins, and polymers. Used in antifreeze or hydraulic fluids. A cryopreservative for cell cultures. Used in the oxidation of thiols and disulfides to sulfonic acids.

Dimethyl sulfoxide (DMSO) is a highly polar aprotic organic reagent that has exceptional solvent properties for organic and inorganic chemicals.

Physical Apppearance: Liquid
Viscosity: 1.1 centipoises (27 °C)
Vapor Density: 2.7 (vs air)
Vapor Pressure: 0.55 hPa at 20 °C, 0.42 mmHg (20 °C)
Refractive Index: n20/D 1.479(lit.)
Solubility: Soluble in water (1 mL DMSO + 1 mL H2O), methanol, acetone, ether, benzene, chloroform

Supplier: HIRSCHMANN

VOL.FLASK 25ML NS12/21 A HOLLOW GLAS WI 1 * 2 items

Supplier: GRANT INSTRUMENTS

The Optima™ range of advanced thermostats can be combined with plastic baths, premium stainless steel baths or refrigeration units. The TX150 and TXF200 thermostats feature a full colour QVGA TFT screen displaying actual and set temperature and clear status icons. The QVGA TFT screen, in combination with the easy to use dial and function keys, allows rapid navigation through the intuitive menu system. Both units have RS232 and USB interfaces and can be programmed via remote PC or laptop using Grant’s versatile Labwise™ software (optional). Additional features include countdown timer, adjustable over-temperature cut-out, visual, audible and programmable high and low temperature alarms. The TX150 has the capacity to store one program with 30 segments. The TXF200 can also be programmed via the user interface and can store up to 10 programs containing 100 segments. The programming interface includes set target temperature with a choice of time to target temperature or temperature ramp speed and an additional programmable relay for on/off control of ancillary equipment or refrigeration units.

Supplier: TOSOH BIOSCIENCE

TSKGel BUTYL-NPR Column, Custom Made Column, 4.6mmID x 10cm 1 * 1 items

Supplier: Biotium

EvaGreen® Dye and high-performance dye-based qPCR master mixes containing EvaGreen® qPCR dye, Cheetah™ HotStart Taq Polymerase, and Forget-Me-Not™ tracking dye. Available with 2-colour tracking or pre-mixed with low or high ROX.

Supplier: Bioss

S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF-kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK. .

Supplier: Thermo Fisher Scientific

DNA purification kit is a simple and rapid system for high quality genomic DNA purification from various sources including: whole blood, serum, cell lines, bacterial cells, plant, and mammalian tissues.

Supplier: witeg Labortechnik

FLASK,PEARSHAPED,25ML,SIDE NECK ANGLED,CNST19/26,SNST19/26,ACC.TO DIN12383 1 * 1 items

Supplier: VITLAB

Volumetric flask, PMP, class B, with screw cap, PP, 250 mL 1 * 2 items

Supplier: Avantor

di-Sodium L(+)-tartrate dihydrate 99.0-101.0%, crystals, BAKER ANALYZED® ACS suitable for standardization of Karl Fischer reagents, J.T.Baker®

Supplier: Hach

Bottle Cap, with inert Teflon® liner for mixing bottle, pk/12 1 * 12 items

Supplier: CONSORT

REDOX STANDARD SOLUTION 500 ML 124 MV 1 * 500 mL

Supplier: VITLAB

Volumetric flask, PMP, class B, with screw cap, PP, 500 mL 1 * 2 items

Supplier: MACRON AVANTOR BRAND

L(+)-Potassium sodium tartrate tetrahydrate 99.0-102.0%, crystals, AR® ACS, Macron Fine Chemicals™

Supplier: GRAM

The unique air distribution system combined with a finned tube evaporator results in excellent temperature consistency for biostorage: the evaporator design eliminates the risk of 'cold walls', which can damage delicate items stored touching the sides of the cabinet. Whilst the air distribution system which directs the cold air down the rear of the cabinet and back up to the evaporator fan at the top, ensures a uniform temperature throughout.

Supplier: MP Biomedicals

RNAintact stabilisation solution is an aqueous sample storage reagent that stabilizes and preserves RNA in samples for extended period at a wide range of storage conditions (−80 to +37 °C).

Supplier: Cytiva

illustra™ MicroSpin™ S-300 HR columns designed for rapid purification of PCR products (>100 bp) from unincorporated primers (<20-mers) and nucleotides using spin-column chromatography.