97383 Results for: "(±)-Tetrahydrofurfuryl+bromide&pageNo=25"

Supplier: MP Biomedicals

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Supplier: MP Biomedicals

Coenzyme A is an essential cofactor in enzymatic acetyl transfer reactions. The principal biologically active forms of pantothenic acid are coenzyme A (CoA) and acyl carrier protein (ACP). In CoA, the business center of the molecule is the pantothenic acid metabolite 4'-phosphopantetheine. Coenzyme A is comprised of 4'-phosphopantetheine linked by an anhydride bond to the nucloetide adenosine 5'-monophosphate. 4'-Phosphopantetheine itself is comprised of pantothenic acid linked at one end, via an amide bond, to beta-mercaptoethylamine, derived from L-cysteine, and at the other end to a phosphate group. The sulfhydryl group of 4'-phosphopantetheine, which is the business end of the coenzyme, forms thioesters with acyl groups producing acyl-CoA derivatives, including acetyl-CoA.
Coenzyme A facilitates removal of lipid peroxides by increasing mobilization of fatty acids, and promote repair of plasma membranes by activating phospholipid synthesis.

Supplier: FRITSCH

starfolded 1 * 1 items

Supplier: Bioss

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodelling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.

Supplier: HAMILTON BONADUZ

The Microlab® 600 dual syringe diluter is a semi-automated liquid handling instrument capable of dilutions up to 1:50000 in a single step. The precision stepper motors provide exceptional positional accuracy across the range of Hamilton bubble-free prime (BFP) syringes from 10 µl to 50 ml volumes. The inert fluid path and the diluent washing of the the tubing between each sample, minimises carry-over for even the most sensitive techniques. The basic controller features a quick start and run screen for priming and programming the diluent and sample volumes, and the controller also displays the graphic pump status with animations of the fluid path and pump status.

Supplier: SHERWOOD SCIENTIFIC INSTRUMENT

Regulated BlueNotes 420 is designed to provide the features required to enable users who need to do so, to operate Sherwood Dual Channel Flame Photometers in a way, compliant with data handling standard 21 CFR Part 11. 1 * 1 items

Supplier: Bohlender

Screw In Stirrer Bearings, For screw in into the center neck of BOLA Reactor Lids for centric guidance of stirrer shafts. A special gasket made of PTFE and an FPM o-ring which is compressed by a GL screw cap made of PPS provide a good sealing of the 1 * 1 items

Supplier: Ahlstrom-Munksjö

Micro-Glass Fiber Filters, MG 1387/1, 257 mm, discs 1 * 50 items

Supplier: HAMILTON BONADUZ

Syringe,10ul,fixed needle,51 x 0.52mm, point style 2.Hamilton. 1 * 1 items

Supplier: KING DISPOSABLES

CONTAINER A7 PS WHITE 120X93X35MM 250CC 1 * 1.000 items

Supplier: HARVARD APPARATUS

96-Well DispoDIALYZER, 96-W MWCO 25K 1 * 2 items

Supplier: VITLAB

Flexible discharge tube for genius / simplex 2, 5 and 10 ml Coiled, made of FEP, approx. 80 cm length, with handle and recirculation valve made of PTFE. Includes handle and assembly instructions. Not suitable for hydrofluoric acid (HF) 1 * 1 items

Supplier: MACHEREY-NAGEL

Amidosulphuric acid for nitrite elimination, pack of 25g NANOCOLOR. 1 * 1 KIT

Supplier: Anicrin

RESERVOIR REAGENT 25ML IRRAD 1 * 1.000 items

Supplier: IKA

Mounting Support AD2,5 For DK2,5.11 1 * 1 items

Supplier: Socorex Isba

Qualitix natural macrotip, 5 mL, graduated, autoclavable, 25x250/bag 1 * 6.250 items

Supplier: BD Medical

The BD CPT™ glass tube provides a single-step, standardised method for the isolation of Peripheral Blood Mononuclear Cells (PBMCs) - lymphocytes and monocytes from whole blood. In a single process step, up to 15 million PBMCs can be isolated within 20 minutes.

Supplier: THERMO LABSYSTEMS LIFE SCIENCE

The Multiskan SkyHigh is a UV/Visible microplate spectrophotometer designed to be convenient and easy to use for virtually any photometric research application, especially DNA, RNA and protein analysis. It is ideal for multi-user environments where a variety of endpoint, kinetic and spectral assays are performed.

Supplier: Bohlender

Screw In Stirrer Bearings, For screw in into the center neck of BOLA Reactor Lids for centric guidance of stirrer shafts. A special gasket made of PTFE and an FPM o-ring which is compressed by a GL screw cap made of PPS provide a good sealing of the 1 * 1 items

Supplier: BELIMED

DIVIDER RK-T H F BASKET 1/4 RK-25H WD230 1 * 1 items

Supplier: Alla France

THERMOMETER PEN -20/+50 1C 1 * 1 items

Supplier: Bohlender

Reactor Lids, Suitable for glass reactors DN 150 with SCHOTT® flat flange. With screw in threads for connection of transition fitti ngs and a center neck NPT 1/2”. 1 * 1 items

Supplier: Cole-Parmer

PTFE coated magnetic stirrerbar 25mm long x 6mm dia. 1 * 5 items

Supplier: Thermo Fisher Scientific

HANDLE 25UL FP FIXED VOLUME 1 * 1 items

Supplier: VARIAN

COLUMN MODULE C18 8U 41.4 X 250 1 * 1 items

Supplier: VELTEK ASSOCIATES

Constructed using CleanPrint 10, Core2Write labels are extremely durable, smear and smudge proof, chemical resistant, and remain pli able in extreme temperatures. All labels can be customized or left blank. 1 * 20 items

Supplier: witeg Labortechnik

BURETTE AUT. ACC. TO PELLET A 25ML AM 1 * 1 items

Supplier: Heidolph Instruments GmbH & Co.KG

Valve tappet GL25 long 165mm for glass-set 1 * 1 items

Supplier: Enzo Life Sciences

Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.

Supplier: Zellstoff-Vertriebs-GmbH & Co. KG

HANDTOWEL 2L GREEN FOLDED ZIG-ZAG 25X23 1 * 3.195 items