PDGF-BB (Platelet-derived growth factor) comprises a family of homo or heterodimeric growth factors, including PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD. Binds to two different transmembrane tyrosine kinase receptors (PDGFR-alpha and PDFGR-beta). Released from degranulating platelets and plays a role in each stage of wound healing. Stimulates mitogenicity and chemotaxis of neutrophils, macrophages, fibroblasts, and smooth muscle cells to the wound site.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free
- Manufactured following GMP guidelines
Enhances proliferation of fibroblasts and their production of extracellular matrix. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Host cell protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative
Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:At or below −20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0.05
- Biological activity:Bioactivity assay: Proliferation of B9 cell, ED50 ≤5 ng/ml, bioactivity ≥WHO standard not available
- Gene ID:Q9HBE4
- Reconstitution instructions:Sterile water at 0,1 - 0,5 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Purity:≥97%
- Molecular weight:15,4 kDa
- Sequence:MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate, pH 7,5
- Nuclease-free:N
- Grade:GMP
- Shipping temperature:Ambient
- Tested applications:Bioassay
: Corning
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: EPPENDORF
: VWR Collection
: VWR Collection
: EPPENDORF
: VWR Collection
: VWR Collection