About this item
Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.
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- Low Endotoxin
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Specifications
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:RatMouse
- Storage conditions:At or below –20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:Bioactivity: No biological activity data is available at this time
- Gene ID:P61148 / P61149
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:ECGF-beta|Beta-endothelial growth factor|HBGF-1|FGF1
- Protein/peptide name:FGF-acidic/GF-1
- Purity:≥95%
- Molecular weight:15,9 kDa
- Sequence:MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate, 75 mM sodium chloride, pH 7,5
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT