Human/Mouse Recombinant TGF-β 3 (from E. coli)

About this item

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

High Quality
Low Endotoxin
Affordable

Shelf life:12 months from date of receipt when stored at 4 °C as supplied.

Caution: For research use only.

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Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Mouse
Storage conditions:
Store at 4 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity assay: Inhibition of IL-4-induced HT-2 cell proliferation, ED50 ≤1 ng/ml, Bioactivity ≥1,0×10⁶ units/mg
Form:
Liquid
Gene ID:
P10600/P17125
Amino acid number:
113/226
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein/peptide name:
TGF-β 3
Purity:
≥95%
Molecular weight:
12,9/25,7 kDa
Sequence:
MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Endotoxin level:
Low
Formulation:
10 mM acetic acid and 20% ethanol at a concentration of 0,25 mg/ml
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
Ice pack
Tested applications:
Bioassay
Purification:
Reducing and non-reducing SDS-PAGE analysis