L(+)-Histidine monohydrochloride monohydrate 98.5-101.0%, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
: L-Histidine monohydrochloride monohydrate, (2S)-(+)-Histidine monohydrochloride monohydrate, L-Histidine hydrochloride monohydrate, (S)-(+)-Histidine monohydrochloride monohydrate, His HCl monohydrate, H-His-OH.HCl.H2O, H-His-OH·HCl·H₂O, L-3-Imidazol-4-ylalanine monohydrochloride monohydrate, L-Histidine hydrochloride hydrate
:5934-29-2
:
:C₆H₉N₃O₂·HCl·H₂O
:MFCD00151027
:1,485 g/cm³ (20 °C)
:209.63 g/mol
:259 °C
:13,04741
:Ambient
- Environmentally Preferable:
- EP/BP - Assay (C6H9N302 HCl) (dried basis):98.5 - 101.0%
- EP/BP - Identification A:Passes Test
- EP/BP - Identification B:Passes Test
- EP/BP - Identification C:Passes Test
- EP/BP - Identification F:Passes Test
- EP/BP - Appearance of Solution:Passes Test
- EP/BP - pH:3.0 - 5.0
- EP/BP - Specific Rotation (.A]2°AO (+):9.2 - 10.6°
- EP/BP-Ninhydrin-Positive Substances-Each:≤0.2%
- EP/BP-Ninhydrin-Positive Substances-Total Impurities:≤0.5%
- EP/BP - Sulfate (S04):≤300 ppm
- EP/BP - Ammonium (NH4):≤0.02%
- EP/BP - Iron (Fe):≤10 ppm
- EP/BP - Loss on Drying at 150 °C:7.0 - 10.0%
- EP/BP - Ash (sulfated):≤0.1%
- JP - Identification:Passes Test
- JP - 0ptical Rotation (+):9.2 - 10.6
- JP - pH:3.5 - 4.5
- JP - Clarity and Color of Solution:Passes Test
- JP - Sulfate (S04):≤0.028%
- JP - Ammonium (NH4):≤0.02%
- JP - Iron (Fe):≤10 ppm
- JP - Related Substances:Passes Test
- JP - Water:7.2 - 10.0%
- JP - Residue on Ignition:≤0.10%
- JP - Assay (anhydrous basis):99.0 - 101.0%
- ChP - Specific Rotation @ 20 °C:8.5 - 10.5°
- ChP - Identification 1 (TLC):Passes Test
- ChP - Identification 2 (IR):Passes Test
- ChP - Acidity or alkalinity (pH):3.5 - 4.5
- ChP - Transmittance of solution:≥ 98.0%
- ChP - Chloride Content:16.7 - 17.1%
- ChP - Sulfates:≤0.02%
- ChP - Ammonium:≤0.02%
- ChP - 0ther amino acids (TLC)(<=0.2%, one spot only):Passes Test
- ChP - Loss on drying @ 105 °C:≤0.2%
- ChP - Residue on ignition:≤0.1%
- ChP - Heavy metals:≤0.001%
- ChP - Arsenic:≤0.0001%
- ChP - Bacterial endotoxin, EU/g:≤6.0
- ChP - Assay, dried basis:99.0 - 101.0%
- ChP - Iron:≤0.001%
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