Ascentis® C8 HPLC columns are optimised to the three terms of the resolution equation: efficiency, retention, and selectivity.

• High purity, type B silica for inertness, reproducibility, and stability
• Modern bonding process optimises bonded phase coverage and maximises stability, while minimising bleed and unwanted secondary interactions
• Compatible with LC-MS and all of today's sensitive instruments and methods
• Scalable sensitivity from analytical to preparative
• High surface area silica for high preparative loading capacity
• Impurity: <5 ppm metals
• Surface coverage: 4,0 µmol/m²

Ascentis® C8 columns often shows similar selectivity to C8 columns, shorter alkyl chains sometimes show different selectivity toward polar compounds because they have solvate differently with the mobile phase and interact differently due to the size and shape of certain molecules. Also C8 reagents are smaller than C18 reagents and have improved primary phase coverage, thereby required less endcapping. Ascentis® C8 has excellent peak shape and very high phase stability.

Ascentis® bonded phases have a wide range of selectivities. It is likely that one or more Ascentis® phase will accomplish any small molecule HPLC separation. Ascentis® products cover all HPLC application areas, including the most sensitive trace-level analyses.