Ascentis® C18 HPLC columns are optimised to the three terms of the resolution equation: efficiency, retention, and selectivity. The classical C18 column is suitable for any method that specifies a C18-type column.

• High purity, type B silica for inertness, reproducibility, and stability
• Modern bonding process optimises bonded phase coverage and maximises stability, while minimising bleed and unwanted secondary interactions
• Compatible with LC-MS and all of today's sensitive instruments and methods
• Scalable sensitivity from analytical to preparative
• High surface area silica for high preparative loading capacity
• Impurity: <5 ppm metals
• Surface coverage: 3,7 µmol/m²

The high surface area gives Ascentis® C18 strong hydrophobic retention and high loading capacity for preparative applications. Ascentis® C18 is low-bleeding for clean ESI and APCI traces. The high retentivity means that the mobile phase can contain a high level of organic modifier.

Ascentis® bonded phases have a wide range of selectivities. It is likely that one or more Ascentis® phase will accomplish any small molecule HPLC separation. Packed in micro- to preparative hardware dimensions, Ascentis® products cover all HPLC application areas, including the most sensitive trace-level analyses.