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Northern Ireland
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Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 550 g/L at 25 °C in water
  APPCZ41940.0416
 :  
Tris(hydroxymethyl)aminomethane (TRIS, Trometamol) 550 g/L at 25 °C in water
  APPCZ41940.0416
 :  

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  • Pk:
    25 kg
  • Seq:
    4283

 

 

  • Assay (Acidim) calc. a.d.s.:
    99,0 -100,5 %
  • Identity according to Pharmacopoeias:
    Passes test
  • pH sol. 10 %:
    10,0 - 11,5
  • pH sol. 5 %:
    10,0 - 11,5
  • Melting range :
    168 - 172 ºC
  • Maximum limit of impurities
    ABS
    at λ a 290 nm, 1 cm 40% sol. in H2O:
    0,1
  • Appearance of solution:
    passes test
  • Insoluble matter in H2O:
    0,025 %
  • Loss on drying at 105 °C:
    0,5 %
  • Residue on ignition (as SO4):
    0,1 %
  • Chloride (Cl):
    0,003 %
  • Microbial Limits:
    2,5 UI/g
  • Bacterial endotoxins:
    1000 cfu/g
  • Total Aerobic Microbial Count (TAMC):
    100 cfu/g
  • Total combined yeast and moulds (TYMC):
    passes test
  • Residual solvents (Ph.Eur/USP):
    1,0 %
  • Related substances (T.L.C.):
    0,001 %
  • Heavy metals (as Pb):
    0,001 %
  • Fe:
    0,001 %
  • Elemental impurities (ICH Q3D)
    Class 1
    Cd:
    0,5 ppm
  • PB:
    0,5 ppm
  • As:
    1 ppm
  • Hg:
    1,5 ppm
  • Class 2A
    Co:
    5 ppm
  • V:
    10 ppm
  • Ni:
    20 ppm
  • Class 2B
    Tl:
    2 ppm
  • Au:
    10 ppm
  • Pd:
    10 ppm
  • Ir:
    10 ppm
  • Os:
    10 ppm
  • Rh:
    10 ppm
  • Ru:
    10 ppm
  • Se:
    15 ppm
  • Ag:
    15 ppm
  • Pt:
    10 ppm
  • Class 3
    Li:
    55 ppm
  • Sb:
    120 ppm
  • Ba:
    140 ppm
  • Mo:
    25 ppm
  • Cu:
    250 ppm
  • Sn:
    600 ppm
  • C:
    25 ppm

 

 

 :
 :121.14 g/mol
 :219,..220 °C
 :171,..172 °C
 :Room Temperature
 :201-064-4
 :77-86-1
 :NH₂C(CH₂OH)₃
 :MFCD00004679