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Specifications
- Antibody type:Primary
- Antigen name:DNA (cytosine-5)-methyltransferase 3A
- Antigen symbol:DNMT3A
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human
- Western blot:Yes
- Epitope:Amino Acid Range = 457-486
- Form:Liquid
- Gene ID:Q9Y6K1
- Antigen synonyms:DNMT3A
- Modification:None
- Storage buffer:Supplied in PBS with 0,09% (W/V) sodium azide
- Molecular weight:102 kDa
- Storage temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0,5 mg/ml
- Shipping temperature:4 °C
- Immunogen:This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human Dnmt3a.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Size:400 µl
- Pk:400 µl
Specifications
About this item
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
Type: Primary
Antigen: DNMT3A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human