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Specifications
- Antibody type:Primary
- Antigen name:Chymotrypsin-like elastase family member 3B
- Antigen symbol:CELA3B
- Clonality:Monoclonal
- Clone:ELTS3B-2
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG1
- Reactivity:Human,Rat,Mouse
- Format:Purified Antibody
- Form:Liquid
- Gene ID:P08861
- Antigen synonyms:CELA3B
- Storage buffer:PBS with 0,1 mg/ml BSA and 0,05% sodium azide
- Storage temperature:Aliquot and Store at 2…8 °C. Avoid freez-thaw cycles.
- Concentration:0,2 mg/ml
- Shipping temperature:4 °C
- Immunogen:A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.
- Purification:Protein G
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
ELISA: 2-4 µg/ml; order BSA free format for coating IF: 1 - 2 µg/ml IHC-P: 1 - 2 µg/ml (1) Optimal dilution of the Elastase 3B antibody should be determined by the researcher.
1. FFPE staining requires boiling tissue sections in 10 mM Tris with 1mM EDTA, pH 9.0, for 10 - 20 min followed by cooling at RT for 20 min.
Type: Primary
Antigen: CELA3B
Clonality: Monoclonal
Clone: ELTS3B-2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat