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Specifications
- Antibody type:Primary
- Antigen name:autophagy related 4B, cysteine peptidase
- Antigen symbol:ATG4B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Western blot:Yes
- Format:Purified Antibody
- Form:Liquid
- Gene ID:Q9Y4P1
- Antigen synonyms:ATG4B
- Storage buffer:PBS with 0,1 mg/ml BSA and 0,05% sodium azide
- Storage temperature:Aliquot and Store at –20 °C. Avoid freez-thaw cycles.
- Concentration:0,5 mg/ml
- Shipping temperature:4 °C
- Immunogen:A recombinant protein fragment from the N-terminal region of ATG4B was used as the immunogen for this antibody.
- Purification:Protein A affinity chromatography
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ‘autophagy-related gene’ ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.
Western blot: 4-6 µg/ml Provided assay concentrations are sµggestions only, ATG4B antibody titration may be required for optimal results.
Type: Primary
Antigen: ATG4B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat