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Specifications
- Antibody type:Primary
- Antigen name:Protein arginine N-methyltransferase 1
- Antigen symbol:PRMT1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Western blot:Yes
- Epitope:Amino Acid Range = 316 - 347
- Form:Liquid
- Gene ID:Q99873
- Antigen synonyms:PRMT1
- Modification:None
- Storage buffer:Supplied in PBS with 0,09% (W/V) sodium azide.
- Molecular weight:42 kDa
- Storage temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:2 mg/ml
- Shipping temperature:4 °C
- Immunogen:This PRMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316 - 347 amino acids from the C-terminal region of human PRMT1
- Purification:This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Pk:400 µl
Specifications
About this item
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
Type: Primary
Antigen: PRMT1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Amino Acid Range = 316-347
Host: Rabbit
Isotype:
Reactivity: Human