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Specifications
- Antibody type:Primary
- Antigen name:thymus cell antigen 1, theta
- Antigen symbol:Thy1
- Clonality:Monoclonal
- Clone:30-H12
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow cytometry:Yes
- Host:Rat
- Isotype:IgG2b
- Reactivity:Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:P01831
- Antigen synonyms:Thy1
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,025 mg
Specifications
About this item
The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.
Type: Primary
Antigen: Thy1
Clonality: Monoclonal
Clone: 30-H12
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse