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Specifications
- Antibody type:Primary
- Antigen name:VHLH
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western blot:Yes
- Epitope:101-200/213
- Form:Liquid
- Gene ID:7428
- Antigen synonyms:von Hippel Lindau syndrome|VHL 1|RCA 1|Protein G7|VHL|VHLH|RCA1|G7 protein|Elongin binding protein|pVHL|VHL1|Von Hippel Lindau disease tumor suppressor|HRCA 1|von Hippel Lindau tumor suppressor|VHL_HUMAN|Von Hippel-Lindau disease tumor suppressor|HRCA1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:24 kDa
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human VHLH/Von Hippel Lindau
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.
Type: Primary
Antigen: VHLH
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/213
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat