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Specifications
- Antibody type:Primary
- Antigen name:ATP1/ATPase Inhibitory Factor 1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:26-106/106
- Form:Liquid
- Gene ID:93974
- Antigen synonyms:ATPIP|ATPase inhibitor protein|AT1_HUMAN|ATP 1|ATPase inhibitor mitochondrial|ATP synthase inhibitor protein|ATPase inhibitory factor 1|MGC1167|MGC8898|mitochondrial|ATP1|ATPI|IP|1|ATPase inhibitor|Inhibitor of F1Fo-ATPase
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:10 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ATPIF1/ATPase Inhibitory Factor 1
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core; and F0, the membrane-embedded protein channel. F1 consists of three Alpha chains and three Beta chains, which are weakly homologous, as well as one Gamma chain, one Delta chain and one Gamma chain. F0 consists of three subunits: a, b and c. A mitochondrial F1-ATPase inhibitor protein, ATPIF1 (ATPase inhibitory factor 1), also known as IP, IF1, ATPI or ATPIP (ATPase inhibitor protein), binds to the C-terminal region of a Beta subunit of the F1-ATPase at low pH values and, via interference of the Beta and Gamma subunit interaction, ATPIF1 regulates the activity of the F1F0-ATPase. This reversible ATPIF1 binding to F1F0-ATPase also occurs on the surface of endothelial cells.
Type: Primary
Antigen: ATP1/ATPase Inhibitory Factor 1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 26-106/106
Host: Rabbit
Isotype: IgG
Reactivity: Human