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Specifications
- Antibody type:Primary
- Antigen name:ITM2C
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:3-88/267
- Form:Liquid
- Gene ID:81618
- Antigen synonyms:CT-BRI3|Cerebral protein 14|ITM3 antibodyNPD018|E25C |E25|Itm2c|BRI3|Integral membrane protein 3|Transmembrane protein BRI3|Integral membrane protein 2C|ITM2C_HUMAN|BRICD2C|BRICHOS domain containing 2C
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:30 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ITM2C
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Type: Primary
Antigen: ITM2C
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 3-88/267
Host: Rabbit
Isotype: IgG
Reactivity: