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Specifications
- Antibody type:Primary
- Antigen name:PPP2R2B/PP2A-B55
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat
- Western blot:Yes
- Epitope:51-130/443
- Form:Liquid
- Antigen synonyms:Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform|PP2A subunit B isoform beta|PP2A PR55B|Protein phosphatase 2 regulatory subunit B|Serine/threonine protein phosphatase 2A neuronal isoform|PP2A subunit B isoform B55 beta|Protein phosphatase 2 regulatory subunit B beta isoform|PP2A subunit B PR55 beta isoform|PR2AB55 beta|PR2APR55 beta|SCA12|2ABB_HUMAN|Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform|PP2A subunit B isoform B55-beta|Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform|Protein phosphatase 2 formerly 2A regulatory subunit B PR 52 beta isoform|PP2A B55beta|SCA 12|PP2A subunit B B beta isoform|Ppp2r2b|PP2A subunit B B55 beta isoform|Beta isoform of regulatory subunit B55 protein phosphatase 2|PP2A subunit B isoform R2 beta|PR52B|PP2A subunit B isoform PR55-beta|PP2A subunit B R2 beta isoform|PP2A subunit B isoform R2-beta|B55 beta|PR2AB beta|PP2A B Subunit B Alpha Isoform|PP2A subunit B isoform PR55 beta|MGC24888|PR55 beta|Protein phosphatase 2 formerly 2A regulatory subunit B beta isoform
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:52 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aå and PP2A. The PP2A catalytic subunit associates with a variety of regulatory subunits. The B family of regulatory subunits (including B55, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity. PP2A-B55, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, is a B subfamily consisting of four B55 isoforms (Alpha, Beta, Gamma and Delta) encoded by four distinct genes.
Type: Primary
Antigen: PPP2R2B/PP2A-B55
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-130/443
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat