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Specifications
- Antibody type:Primary
- Antigen name:HERPUD1
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Western blot:Yes
- Epitope:1-100/391
- Form:Liquid
- Gene ID:9709
- Antigen synonyms:HERPUD1|MMS inducible|SUP|Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1|Methyl methanesulfonate MMF-inducible fragment protein 1|HERP|Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein|HERP1_HUMAN|Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 1|Methyl methanesulfonate MMF inducible fragment protein 1|KIAA0025|M1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:44 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human HERPUD1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
HERPUD1 is a includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.
Type: Primary
Antigen: HERPUD1
Clonality: Polyclonal
Clone:
Conjugation: FITC
Public Immunogen Range: 1-100/391
Host: Rabbit
Isotype: IgG
Reactivity: Rat