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Specifications
- Antibody type:Primary
- Antigen name:Intercellular Adhesion molecule 1
- Antigen symbol:ICAM1
- Clone:15.2
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG1
- Reactivity:Human
- Western blot:Yes
- Neutralisation:Yes
- Gene ID:3383
- Antigen synonyms:ICAM-1|major group rhinovirus receptor|human rhinovirus receptor|BB2|cell surface glycoprotein P3.58|intercellular adhesion molecule 1|P3.58
- Storage temperature:Store undiluted at 2-8°C, protect from light, do not freeze.
- Tested applications:Flow Cytometry
- Size:100 µg
- Pk:100 µG
Specifications
About this item
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).
The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.