Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.
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- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:Bioactivity Assay: NR6R-3T3 Proliferation with 1 µg heparin, ED₅₀ ≤1 ng/ml, Bioactivity ≥1,0×10⁶ units/mg
- Gene ID:P10767
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Protein synonyms:HSTF-2|HST-2|Heparin secretory-transforming protein 2|HBGF-6|Heparin-binding growth factor 6
- Protein/peptide name:FGF-6 (AF)
- Purity:≥95%
- Molecular weight:18,9 kDa
- Sequence:mgTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate and 50 mM sodium chloride, pH 7,5
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
- Tested applications:Bioassay