Dog recombinant IL-2 (from E. coli)

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

Animal-free
Produced from genetically modified E. coli
Monomeric protein containing 136 amino acids

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: This product is for research use only and is not for use in humans.

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Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Dog
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity assay: CTLL-2 cell proliferation, ED50 ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
Gene ID:
Q29416
Reconstitution instructions:
Sterile 10 mM sodium bicarbonate, pH 8.5 at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
Aldesleukin|TCGF|T cell growth factor
Protein/peptide name:
IL-2
Purity:
≥95%
Molecular weight:
15,6 kDa
Sequence:
MAPITSSSTK ETEQQMEQLL LDLQLLLNGV NNYENPQLSR MLTFKFYTPK KATEFTHLQC LAEELKNLEE VLGLPQSKNV HLTDTKELIS NMNVTLLKLK GSETSYNCEY DDETATITEF LNKWITFSQS IFSTLT
Endotoxin level:
Low
Formulation:
20 mM sodium bicarbonate, pH 8,5
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay