Rat Recombinant IL-6 (Animal free) (from E. coli)

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

High quality
Low endotoxin
Affordable

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

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Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Rat
Storage conditions:
−20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤1
Biological activity:
Bioactivity assay: B9 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
Gene ID:
P20607
Reconstitution instructions:
Sterile 10 mM HCl at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
IFN-β2|HSF|BSF-2|B-cell differentiation factor|MGI-2
UniProtKB:
P20607
Protein/peptide name:
IL-6
Purity:
≥90%
Molecular weight:
21,9 kDa
Sequence:
MFPTSQVRRG DFTEDTTHNR PVYTTSQVGG LITYVLREIL EMRKELCNGN SDCMNSDDAL SENNLKLPEI QRNDGCFQTG YNQEICLLKI CSGLLEFRFY LEFVKNNLQD NKKDKARVIQ SNTETLVHIF KQEIKDSYKI VLPTPTSNAL LMEKLESQKE WLRTKTIQLI LKALEEFLKV TMRSTRQT
Endotoxin level:
Low
Formulation:
0,1% Trifluoroacetic Acid (TFA) + 2:1 mannitol to protein
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay