Human recombinant FGF-22 (from E. coli)

Fibroblast growth factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation.

Produced from genetically modified E. coli
Monomeric protein, containing 149 amino acids

It is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF-22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1b receptors. FGF-22 is also required for axonal circuit remodeling after spinal cord injury.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: This product is for research use only and is not for use in humans.

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Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity assay: Currently undetertmined, ED50 ≤Currenlty undetermined, Bioactivity ≥Currently undetermined
Gene ID:
Q9HCT0
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
FGFM
Protein/peptide name:
FGF-22
Purity:
≥95%
Molecular weight:
17,3 kDa
Sequence:
MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTVDCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS
Endotoxin level:
Low
Formulation:
0,1% Trifluoroacetic Acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT