Human Recombinant GDNF (from E. coli)

Supplier: Shenandoah Biotechnology

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Supplier: Shenandoah Biotechnology

About this item

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

High quality
Low endotoxin
Affordable

Caution: For research use only.

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Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity Assay: C₆ proliferation, ED₅₀ ≤3 µg/ml, Bioactivity ≥3,3×10² units/mg
Gene ID:
P39905
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
ATF-1
Protein/peptide name:
GDNF
Purity:
≥95%
Molecular weight:
15,2/30,4 kDa
Sequence:
MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
Endotoxin level:
Low
Formulation:
10 mM Sodium citrate, 100 mM Sodium chloride, pH 4,0
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay