Human Recombinant TGF-B 1 (from CHO cells)

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine that is constitutively produced by thymus tissue and activated peripheral blood mononuclear cells (PBMCs), including dendritic cells. TARC signals through the CCR4 receptor to induce chemotaxis of Type 2 T helper (Th2) cells. TARC is important in asthma and allergic diseases, along with bacterial and viral infections.

High quality
Low endotoxin
Affordable

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

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Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
−20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.1
Biological activity:
Bioactivity assay: Inhibition of IL-4-induced HT-2 cell proliferation, ED50 ≤0,5 ng/ml, bioactivity ≥2,0×10⁶ units/mg
Gene ID:
P01137
Reconstitution instructions:
Sterile 10 mM HCl at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
cartilage-inducing factor|Differentiation inhibiting factor
UniProtKB:
P01137
Protein/peptide name:
TGF-beta1
Purity:
≥95%
Molecular weight:
12,8/25,6 kDa
Sequence:
ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Endotoxin level:
Low
Formulation:
0,1% trifluoroacetic acid (TFA) and trehalose in a 20:1 trehalose to protein ratio
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay