Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. Human and mouse IL-5 show cross-reactivity.
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- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:Bioactivity assay: TF-1 cell proliferation, ED50 ≤0,25 ng/ml, Bioactivity ≥4,0×10⁶ units/mg
- Form:Lyophilised
- Gene ID:P05113
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:Eosinophil differentiation factor|TRF|B-cell differentiation factor I
- Protein/peptide name:IL-5
- Purity:≥95%
- Molecular weight:13,3/26,6 kDa
- Sequence:MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
- Endotoxin level:Low
- Formulation:10 mM sodium glycinate, pH 8,5
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
- Tested applications:Bioassay