The melanocortin receptors are members of the G protein-coupled receptor superfamily. Their ligands, the melanocortins, are peptides consisting of µ-, β- and γ-melanocyte stimulating hormone and adrenocorticotropic hormone. MC3R binds all melanocortins with equal affinity. Agouti-related protein (AGRP) is the high affinity endogenous antagonist of MC3R. It is expressed in the brain, placenta, and gut tissues, but not in the adrenal cortex or melanocytes.
- For Immunohistochemistry, Western Blot
Recognizes human, rat and mouse MC3R.
Application notes: To Lyophilize antibody, add 50µl or 200µl (depending on which size was purchased) of deionized water. Application notes: To Lyophilized peptide, add 100µl of deionized water.
Type: Primary
Antigen: MC3R
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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