About this item
Calreticulin (CRT) is a multifunctional, multi-compartmental protein most abundant in the ER lumen. CRT contains the ER-retrieval sequence, KDEL, and has been best characterized as a soluble molecular chaperone of new or misfolded proteins and a Ca2+- binding protein. Both CRT and its membrane bound homolog, Calnexin (CNX) interact with proteins and glycoproteins that have monoglucosylated N-glycans. The CRT/CNX cycle promotes correct folding, inhibits aggregation of folding intermediates, blocks premature oligimerization, regulates ER degradation, and provides quality control by preventing incompletely folded glycoproteins from exiting to the Golgi complex.
- For Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Recognizes human, mouse, rat, bovine, and dog calreticulin. Detects a band of ~63kDa by Western blot.
Type: Primary
Antigen: CRP55
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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Specifications
- Catalog No:
- ENZOADISPA600D
- ENZOADISPA600J
- ENZOADISPA600F
- Antigen symbol:
- CRP55
- CRP55
- CRP55
- Antigen name:
- Calreticulin
- Calreticulin
- Calreticulin
- Antigen synonyms:
- CRT|FLJ26680|CALR|cC1qR|SSA|endoplasmic reticulum resident protein 60|HEL-S-99n|RO
- CRT|FLJ26680|CALR|cC1qR|SSA|endoplasmic reticulum resident protein 60|HEL-S-99n|RO
- CRT|FLJ26680|CALR|cC1qR|SSA|endoplasmic reticulum resident protein 60|HEL-S-99n|RO
- Antibody type:
- Primary
- Primary
- Primary
- Clonality:
- Polyclonal
- Polyclonal
- Polyclonal
- Reactivity:
- Human
- Host:
- Rabbit
- Rabbit
- Rabbit
- Western blot:
- Yes
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- Yes
- Form:
- Liquid. In PBS containing 50% glycerol and 0,09% sodium azide.
- Liquid. In PBS containing 50% glycerol and 0,09% sodium azide.
- Liquid. In PBS containing 50% glycerol and 0,09% sodium azide.
- Purification:
- Protein A affinity purified
- Protein A affinity purified
- Protein A affinity purified