Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.
- For Immunocytochemistry, Western Blot
Recognizes mouse and rat agrin. Detects a band of ~100kDa by Western blot.
Type: Primary
Antigen: AGRN
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Mouse
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- Catalog No:
- ENZOADIAGR530F
- ENZOADIAGR530D
- Antigen symbol:
- AGRN
- AGRN
- Antigen name:
- Agrin
- Agrin
- Antigen synonyms:
- Agrin C-terminal 110 kDa subunit|AGRN|CMS8|Agrin N-terminal 110 kDa subunit|RP23-139J18.2|C90|Agrin C-terminal 90 kDa fragment|AGRIN|Agrin C-terminal 22 kDa fragment|Agrin|CMSPPD|C22
- Agrin C-terminal 110 kDa subunit|AGRN|CMS8|Agrin N-terminal 110 kDa subunit|RP23-139J18.2|C90|Agrin C-terminal 90 kDa fragment|AGRIN|Agrin C-terminal 22 kDa fragment|Agrin|CMSPPD|C22
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Reactivity:
- Mouse
- Host:
- Mouse
- Mouse
- Isotype:
- IgG2a
- IgG2a
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- Form:
- Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
- Purification:
- Protein G affinity purified