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- Antibody type:Primary
- Antigen name:15-deoxy-delta12,14-Prostaglandin J2
- Antigen symbol:15-Deoxy-Delta-12
- Clonality:Polyclonal
- ELISA:Yes
- Host:Rabbit
- Reactivity:Multiple
- Seq:02
- Form:Liquid. In PBS containing 1,0 mg/ml Rabbit IgG and 0,1% sodium azide.
- Purification:Sodium sulfate precipitation purified
- Pk:100 µl
15-deoxy-Δ12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Δ12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the γ isoform of the peroxisome proliferators-activated receptor (PPAR-γ). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-γ-independent mechanism mediated by the generation of reactive oxygen species (ROS).
- For ELISA, Flow Cytometry
Species independent.
Type: Primary
Antigen: 15-Deoxy-Delta-12
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: pan