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Specifications
- Antibody type:Primary
- Antigen name:ORAI calcium release-activated calcium modulator 1
- Antigen symbol:ORAI1
- Clonality:Monoclonal
- Clone:3F6H5
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Format:Purified Antibody
- Form:Liquid
- Gene ID:84876
- Antigen synonyms:ORAI1 Antibody [3F6H5] : IMD9, ORAT1, CRACM1, TMEM142A
- Molecular weight:Predicted: 33 kDa
Observed: 56 kDa - Storage temperature:ORAI1 monoclonal antibody can be stored at -20˚C, stable for one year.
- Concentration:1 mg/mL
- Shipping temperature:4°C
- Immunogen:Mouse monoclonal ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.
- Purification:ORAI1 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
- Size:100 μg
- Pk:100 µG
Specifications
About this item
ORAI1 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one fo rm of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
ORAI1 antibody can be used for detection of ORAI1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Type: Primary
Antigen: ORAI1
Clonality: Monoclonal
Clone: 3F6H5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human, Mouse, Rat