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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Human
- Tag sequence:Fc Tag
- Storage conditions:Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
- Protein synonyms:MDC|Macrophage-derived Chemokine|C-C Motif Chemokine 22|CC Chemokine STCP-1|Stimulated T Cell Chemotactic Protein 1|Small-inducible Cytokine A22
- Protein/peptide name:CCL22
- Purity:>98% (SDS-PAGE)
- Sequence:25-93
- Formulation:Lyophilized from 0.2um-filtered solution in PBS.
Specifications
About this item
CCL22, also named stimulated T cell chemotactic protein (STCP1), is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilisation in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.