Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:GST tag
- Storage conditions:Stable for at least 1 year after receipt when stored at −20 °C. Reconstituted solutions can be kept at 4 °C under sterile conditions for one week or should be frozen in aliquots at −20 °C.
- Protein synonyms:Endonexin II|Calphobindin I|Placental Anticoagulant Protein I|Vascular Anticoagulant-alpha|Lipocortin V|Annexin A5
- Protein/peptide name:Annexin V
- Purity:>95% (SDS-PAGE)
- Formulation:Lyophilized, In PBS, pH 7.4.
Specifications
About this item
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibits the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the 'annexin V affinity assay' to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Fusion-Tag: GST tag
This recombinant proteins is for research use only.